Risk Factors Associated with Limb Amputation in a Referral Hospital in Benue State Nigeria
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2015, Vol 10, Issue 10
Abstract
Background: Trauma, diabetes mellitus and peripheral vascular disease are age old known risk factors associated with amputation. However, at the Nongu Kristi U Sudan hen Tiv (NKST) Rehabilitation hospital, Mkar, Gboko, Benue state Nigeria, HIV/AIDS is increasingly becoming a major risk factor for upper limb amputation, and this is investigated in this study. Objectives: To determine the risk factors involved in amputation in a referral hospital located in Benue State Nigeria. Methods: A Descriptive cross sectional study design was adopted for this study where the pre-operative assessments for HIV testing, serum Fasting Blood Sugar (FBS) level, Full Blood Count (FBC), CD4 counts, Hepatitis B and C antigens were carried out using standard laboratory investigation techniques. Dopplar ultrasonographic assessment of the affected limb was done preoperatively to determine the nature and level of vascular obstruction while post-operative histocytology of the amputated stump was performed to determine the pathology at the Benue State University. Data obtained were entered into a profoma already designed for the study while statistical analysis was performed with the aid of SPSS (Version 20) with level of significance set at 95%. Results: A total of 60 patients booked for amputation within the study period were enrolled for this study. Majority were Males 41 (68.3%), out of which amputation cases in individuals below 10 years of age were mainly due to trauma (8.3%). The age range of 21-40 years recorded the highest number of amputations 24 (40%). In the female patients, trauma was responsible for 8 (42.1%) cases while HIV was associated with 1 (5.3%) of all amputations. In males trauma and HIV/AIDS were indications in 25 (61%) and 10 (24.4%) respectively. Other risks factors in males responsible for amputation were diabetes 2 (4.9%) and vascular diseases 1 (2.4%). In females, diabetes mellitus was associated with 6 (31.5%) of amputations. There is a statistically significant difference in the indication for limb amputation in male and female patients where HIV/AIDS was significantly higher in males 10 (24.4%) than in females (x2 = 13.1; p= 0.01). Lower limbs 49 (81.7%) amputations were more than upper limbs 11 (18.3%) amputations. This study revealed that HIV/AIDS ranked second as an indication for upper limb amputations although trauma was the main indication for most upper limb amputations. Conclusion: This study showed that trauma remains the predominant risk factor for amputation, however HIV/AIDS is emerging as a major indication for upper limb amputation.
Authors and Affiliations
E. T. Amaefula, I. O. G. Owoeye, N. J. Kortor
Clinical Pattern of Dermatoses in Patients with Chronic Kidney Disease in Ile-Ife, Nigeria
Bacground: Dermatoses are common in patients with chronic kidney disease (CKD). These dermatoses vary from the more common xerosis, pruritus, hyperpigmentations, to the less common manifestations such as nephrogenic syst...
Trisomy 21: Genetic Analysis Aided Diagnosis
Being the most common yet rare genetic syndrome in the field of dentistry Trisomy 21 also known as the Down’s syndrome named after John Langdon Down has its own importance in dentistry. It has characteristic physical, ge...
Antioxidant and Anti-malarial Properties of Catechins
Aims: This research was performed to evaluate the antioxidant and anti malarial activities of various catechins including catechin (C), epicatechin (EC), catechin-gallate (CG), gallocatechin-gallate (GCG), epigallocatec...
Abdominal Aortic Hypoplasia, a Rare Cause of Hypertension
Hypoplasia of the abdominal aorta is an exceedingly rare vascular abnormality. Congenital, acquired, infectious and inflammatory etiologies have been described. Hypertension is the most common presenting symptom. Besides...
Vitamin A Status of Steady State Sickle Cell Anaemia Patients Compared to Normal Control in Maiduguri North Eastern Nigeria
Sickle cell anaemia is an inherited disorder of haemoglobin characterized by sickled red blood cells and increased destruction of these cells. Antioxidants protect cells from the damaging effects of free radicals. The ai...