Risk factors contributing to hypoglycemia among diabetes mellitus patients: a systematic review and meta-analysis
Journal Title: Journal of Public Health and Development - Year 2025, Vol 23, Issue 2
Abstract
Hypoglycemia is a dangerous, life-threatening condition affecting various populations, specifically diabetes mellitus (DM) patients. The condition has been reported to be influenced by several factors, such as gender, age, and body mass index (BMI). However, previous studies exploring these factors have yielded varying results, indicating the need for further investigations. This study aimed to identify factors contributing to hypoglycemia among DM patients through a systematic review and meta-analysis. The study procedures were carried out using PRISMA 2020 statement review reporting standards. In addition, a literature search was performed on four databases, including Pubmed, Scopus, Google Scholar, and Crossref, using Publish or Perish version 8 software. After the search, a total of 12 original articles were obtained based on the eligibility criteria. The results showed that eight factors significantly contributed to incidence of hypoglycemia, including elderly (OR 11.05; CI95%: 9.20-13.27), insulin use (OR 5.60; CI95%: 4.66-6.74), uncontrolled blood glucose (OR 4.07; CI95%: 3.41-4.85), have history of hypoglycemia (OR 3.52; CI95%: 2.27-5.45), overweight/obese (OR 2.63; CI95%: 1.89-3.64), sulfonylurea use (OR 1.98; CI95%: 1.37-2.85), longer DM duration (OR 1.29; CI95%: 1.20-1.38), and male gender (OR 1.31; CI95%: 1.21-1.42). Based on the results, the eight influential factors could be categorized into three domains, including medication-related hypoglycemia, non-modifiable medical conditions, and lifestyle-related hypoglycemia.
Authors and Affiliations
Made Krisna Adi Jaya, Fita Rahmawati, Nanang Munif Yasin, Zullies Ikawati
Keywords
Related Articles
- EP ID EP765335
- DOI 10.55131/jphd/2025/230223
- Views 10
- Downloads 0
Performance of the District Health Boards within the district health system in Chiang Mai Province, Thailand
The objectives of this cross-sectional study were to examine the performance of the District Health Boards (DHBs), and to investigate factors affecting DHB performance within the district health system in Chiang Mai Prov...
Barriers and facilitators to implementation of smoke-free area policy in public places: a scoping review
Enforcing laws requiring smoke-free areas in different locations is one way the government can lower cigarette consumption and exposure to cigarette smoke. The purpose of this study was, thus, to examine and summarize st...
Characteristics of mask adherence in low and medium-income countries and high-income countries: Results from round II of the global COVIDiSTRESS survey
Many studies have connected mask-wearing during the coronavirus pandemic to various characteristics and beliefs; yet much of this research has been conducted in wealthy countries in the Global North. Performing a seconda...
Information behaviour and factors influencing family planning knowledge of Myanmar ethnic migrants: a qualitative study
The accessibility to quality family planning (FP) information and counselling for Myanmar ethnic migrants in Thailand is questionable. Inadequate knowledge and lack of informed choice to practice FP...
Disparities in sugar-sweetened beverage expenditures: insights from Indonesian urban and rural households
Excessive consumption of sugar-sweetened beverages (SSBs) poses a significant health risk because of their poor nutritional content. This study investigates SSB expenditure among Indonesian households with the goal to an...