Risk Factors of Severe Healthcare-Associated Adverse Events in a Tunisian Hospital: Results of a Case-Control Study
Journal Title: Saudi Journal of Medicine - Year 2018, Vol 3, Issue 8
Abstract
Abstract:Adverse events (AE) are an ongoing challenge in healthcare.Apart from having a significant impact on patient morbidity and mortality, AE also result in increased healthcare costs due to longer hospital stays.However, little is known about AE occurrence and their risk factors in Tunisian healthcare system.To determine the incidence of severe adverse events (SAEs) and identify risk factors associated with SAE during hospitalization in a Tunisian University Hospital.A case-control study with incident cases was conducted including all patients hospitalized in the Teaching Hospital FarhatHached within a one-month period in 13 clinical units. Medical records for caseswere selected by using stratified random sampling. The sample size was proportional to the number of admissions in each of 13 clinical departments. Controls were matched by the service and the duration of hospitalization preceding the appearance of SAE. Risk factors were collected and analyzed by conditional stepwise logistic regression.Overall, 304 controls were matched to cases, totalizing 456 patients. Multivariate conditional stepwise logistic regression analysis showed that night-time admission, hospitalization in the last six months, difficulty of communication, longer surgical operation, biopsy, presence of at least two medical devices, exposure to peripheral venous catheter,exposure to more than four medications and blood transfusion were considered as independent risk factors of SAE occurrence. Our results highlighted care-related risk factors such as catheters, blood transfusion and polymedication, which underlined the need to strengthen the care safety by focusing efforts especially in the field of hospital hygiene and infection control as well as pharmacovigilance. Keywords: Adverse event Risk factor Patient Safety Healthcarequality.
Authors and Affiliations
Nabiha Bouafia, Olfa Ezzi, Asma Ammar, Iheb Bougmiza, Fathi Bahri, Mondher Letaief, Pascal Astagneau, Mansour Njah
Keywords
Related Articles
- EP ID EP399892
- DOI -
- Views 55
- Downloads 0
Ramadan Fasting: Effect on the Metabolic Profile of Healthy Medical Students in north east, Nigeria
Abstract:The voluntary religious undertaking of fasting has attracted scientific, religious and popular interest due to its supposed health benefits. The objective of this study was to determine the effects of intermitte...
Prevalence ofanemia among Schedule Caste Women: A Hospital-Based Study in Eastern Nepal
Abstract:A hospital based study was carried out in eastern Nepal to determine prevalence of anemia in different age group among schedule caste women (20->70) years age Population. Cyanmethemoglobin method was used to det...
Trend of using of smart phones by medical students
Abstract: Medical education has undergone major changes from teacher centered to student centered, from discipline based to integrated, from hospital based to community based curriculum and is more focused on formative l...
Acute Cytolytic Hepatitis Induced by Allopurinol
Allopurinol is a drug indicated for the treatment of hyperuricemia. Its hepatic toxicity is rare. This is a case report about acute cytolytic hepatitis caused by allopurinol in a 62-year-old.
Nominative Drug-Dispensing System in Hospital: Literature Review and Sharing of Experience
Abstract:Once prescribed, within a hospital structure, the drug will follow a complex circuit, involving many intermediates, human and technical, and leading to the drug administration and its monitoring. From the point...