Risk of Malignancy Index in the Preoperative Evaluation of Patients with Adnexal Masses among Women of Perimenopausal and Postmenopausal Age Group
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 9
Abstract
INTRODUCTION: In some ovarian cancer especially in early stage, risk of malignancy index (RMI) is proposed for clinical use and is found to yield better result indiscriminating between benign and malignant ovarian tumours than any single test of morphologic Ultrasound scores, CA 125, or menopausal status. MATERIALS AND METHODS: 100 patients were taken up into 2 groups of 50 each to depending on RMI, group A having patients with RMI>200 (n=50), group B having patients with RMI<200 (n=50). RESULTS: Analysis shows that there is 1.6 times more chance of a tumour being malignant in postmenopausal women than in peri-menopausal women with adnexal mass. There is statistically significant increased incidence of malignancy in postmenopausal women (p value= 0.0265). The study finds the best cut-off value for RMI is at >230. DISCUSSION: Comparison of all parameters, CA-125, USG score and RMI to predict malignancy show, CA125 has the highest sensitivity and lowest specificity. The ROC curves of the 3 tests and AUC under these curves show, the highest AUC was observed with RMI and lowest with USG score. So performance of RMI is the best among all parameters to predict malignancy in adnexal masses.
Authors and Affiliations
Daibi Guin, Pallab Kumar Mistri, Bandana Biswas
Keywords
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