Rituximab Treatment in a Patient with Active Graves’ Orbitopathy and Psoriasis
Journal Title: TÜRK OFTALMOLOJİ DERGİSİ - Year 2017, Vol 47, Issue 1
Abstract
Management of Graves’ orbitopathy remains an important therapeutic challenge. Current therapeutic modalities are unsatisfactory in about one third of patients. Rituximab is a monoclonal antibody against CD20 antigen that is expressed in mature and immature B cells. Early experience with rituximab suggests that it is a promising alternative therapy for Graves’ orbitopathy. Here we report a case of a 49-year-old woman with Graves’ orbitopathy and psoriasis. The patient received 2 infusions of 1 g rituximab 2 weeks apart. Although there was improvement in inflammatory signs of the disease, proptosis did not change after the treatment.
Authors and Affiliations
Tülay Şimşek, Nilgün Yıldırım, Belgin Efe, Nur Kebapçı
Keywords
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- EP ID EP236335
- DOI 10.4274/tjo.26780
- Views 137
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