Role of antibiotic loaded acrylic bone cement in orthopedic infection
Journal Title: National Journal of Clinical Orthopaedics - Year 2018, Vol 2, Issue 3
Abstract
Introduction: Local antibiotic delivery with antibiotic loaded acrylic bone cement has been used extensively in the management of chronic osteomyelitis and implant related infections. It is considered the gold standard for treatment of musculoskeletal infections (Nelson, 2004). Over the past few decades, attempts have been made to prevent and cure orthopedic implant infections by incorporating antibiotics in polymethylmethacrylate bone cements, in primary and revision surgery. Antibiotic loaded bone cement (ALBC) is popular as it is a proven way to deliver high concentrations of the drug locally, even to avascular areas that are inaccessible by systemic antibiotics. This article review the role of antibiotic loaded acrylic bone cement beads in orthopaedic trauma. Materials & Methods: This is a Prospective, Non Randomized study carried out in 40 patients posted for orthopaedic procedures. For evaluating the functional outcome of treatment we used the Asepsis Wound Score. Total duration of study is 6 to 9 months. Results: The mean age of the patient was 40 years (range 20-50 yrs). Incidence of fracture was observed maximum between 40- 50 years of age. Among the 40 cases, males were predominant. We observed predominance Staphylococcus Organism in Pus Culture. Out of 40 cases 53% cases was open fractures and 70% cases were RTA. Conclusion: The theoretical advantages of antibiotic-impregnated cement and cement beads in the treatment and prophylaxis of orthopedic infections are supported by the results of some studies but Evidence of their efficacy, particularly in comparison with those of systemic antibiotics or with those of antibiotic-impregnated cement or beads in combination with systemic antibiotics, have not been firmly established. In our study there was marked decrease in infection rate by using antibiotic cemented beads but certain infection like Chronic osteomyelitis is often a lifelong disease. Despite all of the advances in antibiotic and operative treatment, osteomyelitis remains difficult to treat.
Authors and Affiliations
Dr. Punit J Tank, Dr. Vishal A Pushkarna, Dr. Sheetal Gamit
Keywords
Related Articles
- EP ID EP506911
- DOI -
- Views 50
- Downloads 0
To study the outcome of intercondylar fractures of distal humerus using dual plating and its functional outcome
Introduction: Distal humeral fractures account for approximately 2%–6% of all fractures and for approximately 30% of all elbow fractures [1]. The complex anatomy of the distal end of the humerus, with its unique orientat...
To evaluate the ponseti method of manipulation for treatment of rigid, neglected, recurrent cases of clubfoot in children between age of 02-10 years
A prospective study to determine effectiveness of Ponseti method in correcting clubfoot in children aged 2-10 years and failed or recurrent clubfoot in children aged 2-10 years was done at Department of Orthopaedics & Tr...
Results of uncemented THR in Indian patients in Indian conditions
Introduction: The hip joint is the most important joint of the body as it enables a person to assume various postures. Diseases of this joint are always alarming because if untreated, produces serious disability, for thi...
Assessment of outcomes of locking compression plates for fractures of distal end of femur
Objective: To evaluate the result of locking compressive plate in different types and severity of distal femoral fractures both clinically and radiologically. Methods: 40 male and 10 female patients aged 18 to 85 (mean 3...
To study the functional outcome of the fracture of proximal tibia and the duration of union in proximal tibial fracture treated with LCP
Introduction: The knee joint is one of the three major weight bearing joints in the lower extremity. Fractures of proximal tibia that extend into the knee joint are termed as the tibial plateau or condylar fractures. Pro...