Role of Antioxidant-Rich Nutraceutical on Body Weights and Mean Arterial Blood Pressure of Salt-Induced Hypertensive Rats
Journal Title: International Journal of Biochemistry & Physiology - Year 2017, Vol 2, Issue 1
Abstract
Hypertension or high blood pressure is a medical condition in which blood pressure in the vessels is persistently elevated. The study aim to formulate an antioxidant rich nutraceutical from locally available food stuff (onion, garlic, ginger, tomato, lemon, palm oil, water melon seeds) and investigate their effects on blood pressure and body weight in salt-induced rats. The rats were placed on 8% salt diet for 6 weeks and then supplementation and treatment with nutraceutical and nifedipine in the presence of salt diet for additional 4 weeks. Feeding rats with salt diet for 6 weeks increased blood pressure and body weight of the salt-loaded rats relative to control. Both supplementation and treatment (nifedipine) lowered the blood pressure but only supplementation lowered the body weight. Antioxidantrich nutraceutical might be beneficial in the managements of patients with hypertension and obesity.
Authors and Affiliations
Lawal N
Keywords
Related Articles
- EP ID EP396066
- DOI 10.23880/ijbp-16000114
- Views 53
- Downloads 0
Nutritional Ketosis Condition and Specific Ketogenic Diet, May Benefit Cancer Patients as an Alternative Treatment by Sudden Change in the Metabolic State of Cancer Cells
Cancer disease is the second cause of death in the United States and world-wide. Most Researchers estimate that 595,690 of American people will die from cancer at the end of the year 2017. That means 1,600 deaths/day app...
Hypoglycaemic Mechanism of Manosrin from Anisopus Mannii N. E. Br.
Medicinal Plants from various parts of the world have been tested for their hypoglycaemic properties and other related ailments. These have resulted into the isolation and purification of novel compounds which have been...
PKA Subunits in the Human Pathogen Paracoccidioides: An in Silico Approach
Paracoccidioides brasiliensis and P. lutzii is the causative agent of paracoccidioidomycosis, a primary systemic mycosis with different clinical manifestations. Infection occurs when hypha-fragments or spores are inhaled...
Association of rs2231142 with Serum Uric Acid among the Nepalese Patient Visiting the Tertiary Care Hospital
Background: Uric acid is the byproduct of purine nucleotide catabolism. Hyperuricemia is an excess of uric acid in the blood which leads to gout. The single nucleotide polymorphism, C-to-A mutation rs223114 in ABCG2 gene...
Investigation Effect of Free Radical Generated from Cement Dust on Antioxidant Enzymes Activities on Cement Factory Workers
This study investigated effects of cement dust on antioxidant enzymes activities of Obajana Cement factory workers. Sixty (60) workers in different units/sections exposed to cement dust and controls (unexposed to cement...