Role of C-peptide in Altered Lipid Profile among Apparently Healthy Adults of Vijayapura City, Karnataka 

Journal Title: Journal of Krishna Institute of Medical Sciences University - Year 2016, Vol 5, Issue 2

Abstract

Background: C-peptide is produced in equimolar concentration during insulin production as inactive molecule by beta islet cells of Langerhans. C-peptide is most useful biomarker of endogenous insulin production. Aim and Objectives: To predict metabolic syndrome in advance by estimation of C-peptide and lipid profile in healthy adults. Material and Methods: Serum C-peptide, fasting blood glucose and lipid profile of 128 healthy individuals were estimated. Adults in the age group of 18 to 60 years of both sexes were included in study. Results: C-peptide levels were increased in 27%, Serum cholesterol in 30%, LDL Cholesterol in 55% and triglyceride levels in 21% of healthy individuals. Significant correlation was observed between C peptide, age, serum cholesterol, LDL and cholesterol LDL ratio in male subjects only. In our study group most of the subjects (both males and females) fell in overweight group. Conclusion: Cpeptide level and lipid profile may be considered as useful biomarkers to predict type 2 diabetes mellitus in advance, possibly due to insulin resistance.

Authors and Affiliations

Chandrahas M. Kulkarni , Sumangala M. Patil

Keywords

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  • EP ID EP154109
  • DOI -
  • Views 79
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How To Cite

Chandrahas M. Kulkarni, Sumangala M. Patil (2016). Role of C-peptide in Altered Lipid Profile among Apparently Healthy Adults of Vijayapura City, Karnataka . Journal of Krishna Institute of Medical Sciences University, 5(2), 79-86. https://europub.co.uk/articles/-A-154109