Role of diffusion weighted imaging and apparent diffusion coefficient in diagnosing abdominal and pelvic pathologies in 3T MRI: A retrospective cross-sectional study
Journal Title: Medpulse International Journal of Radiology - Year 2019, Vol 9, Issue 2
Abstract
Background: Diffusion weighted imaging (DWI) and Apparent Diffusion Coefficient (ADC) mapping have been widely used for various applications in neuro imaging, but not exploited enough in abdominal imaging in the present clinical scenario. So, our aim was to identify the specificity of DWI and ADC mapping in characterizing and abdominal or pelvic pathology as benign or malignant and its accuracy as an alternate imaging technique in patients whom MR contrast is contra indicated. Material and methodology: A Retrospective Cross-sectional Study was conducted by collecting secondary data from patients with abdominal or pelvic pathology who had undergone Plain MRI Abdomen or MRI pelvis including DWI and ADC sequences over a period of 9 months in our department of Radiodiagnosis. The MRI final diagnoses were correlated with the histo-pathological reports for all except simple cystic lesions. The ADC values were documented for each case. The Frequency, Percentage, Range, sensitivity, specificity, Positive Predictive Value, Negative Predictive Value and over all Accuracy of the study comparison were calculated using Fishers exact test. Results: Out of the 40 cases included in the study, 22 diagnosed cases of malignant lesions in MRI were confirmed to be malignant in histopathological correlation and 13 out of 14 cases which were diagnosed to be benign were confirmed the same on histopathological correlation. In our study we found that ADC values for diagnosed malignant lesions were in the range of 0.43x10-3 – 0.74x10 -3mm2/sand that for the benign lesions were between 0.79x10-3 – 1.34x10 -3mm2/s and that for simple cystic lesions were in the range of 2.4x10-3 -3.1x10-3mm2/s. Conclusion: Diffusion weighted imaging - Apparent diffusion coefficient mapping has high accuracy in characterizing a pathology as benign or malignant and is highly beneficial in patients whom MR contrast study is contra indicated.
Authors and Affiliations
Aswathi Prakash, Adarsh K. M, Devadasa Acharya K, Ravichandra G, Vinayaka U S, Jomon Sunny
Keywords
Related Articles
- EP ID EP539549
- DOI 10.26611/10139211
- Views 165
- Downloads 0
CT angiographic analysis of patients with aortic aneurysm
Background: Multidetector computed tomographic (CT) angiography is routinely performed for the diagnosis and evaluation of thoracic aortic aneurysms. It demonstrates not only the lumen of an aneurysm, but CT angiography...
Assessment of changes in brain metabolites in patients with type-2 diabetes mellitus using proton magnetic resonance spectroscopy – One year hospital based cross sectional study
Diabetes mellitus is a chronic and potentially disabling disease which is reaching an epidemic proportion in many parts of the world and a major growing threat to global public health. Diabetes Mellitus has evolved into...
MRI assessment of non traumatic intracranial bleed
Nowdays MRI has turned into the strategy of decision for surveying the age of an intracranial discharge. On MRI intensity signal of intracranial hemorrhage is influenced by multiple factors including: (a) age, location,...
Comparative study of carotiddoppler with contrast enhanced MRA in patients with stroke
Background: Cerebrovascular accident or stroke is one of the most common causes of death. Ultrasonography of the carotid arteries is an easily available, costeffective, noninvasive method of evaluation. Treatment of stro...
Role of computed tomography imaging in evaluation of stroke
Background: A stroke is the acute neurological injury occurring as a result of one of this pathological process and manifests either as cerebral infarction or hemorrhage. Identification of risk factors for stroke as well...