ROLE OF EARLY CLEAVAGE IN PREDICTING SUCCESS OF INTRA CYTOPLASMIC SPERM INJECTION IN ASSISTED REPRODUCTIVE TECHNOLOGIES
Journal Title: International Journal of Medical Research & Health Sciences (IJMRHS) - Year 2014, Vol 3, Issue 3
Abstract
Aim and Objective: The present study is aimed to carry out the impact of early cleavage over late cleavage in assessing the pregnancy outcome using of Intra Cytoplasmic Sperm Injection (ICSI) in assisted reproductive technologies. Materials and Methods A total of 154 patients enrolled for Intra Cytoplasmic Sperm Injection (ICSI) fulfilling the selection criteria were recruited for the study at a tertiary care assisted reproductive centre. ICSI was performed 3–5 h after oocyte aspiration with the prepared sperm. All embryos were checked for early cleavage at 27 hours post intra cytoplasmic sperm injection. They were divided into two groups. Group IEmbryos which cleaved before 27 hours after Intra Cytoplasmic Sperm Injection (ICSI). Group II- Embryos which cleaved after 27 hours. The pregnancy rates were compared between the two groups. Results: All the 154 patients were analysed. There was no difference in the mean age, duration of ovarian stimulation, number of oocytes retrieved, fertilization, cleavage rates and embryo quality between the two groups. Early cleavage was observed in 98 patients (63.64 %). Late cleavage was observed in 56 patients (36.36%). The clinical pregnancy was confirmed in 59 patients (60.20%) in Group I and 20 patients (35.71%) in Group II which was statistically significant P <0.001. Conclusion: Early cleavage is a strong predictor of embryo quality and can predict ICSI outcome.
Authors and Affiliations
Manjula Gopalakrishnan| Embryologist, Department of Reproductive Medicine, Sri Ramachandra University, Chennai, Corresponding author email: manjuladaniel2000@yahoo.co.in, manjula2000srmc@gmail.com , Sanjeeva Reddy Nellapalli| Professor & Head, Department of Reproductive Medicine, Sri Ramachandra University, Chennai, Muthiah sinvaniah surulimuthu| Embryologist, Kanmani Fertility clinic, Chennai
Keywords
Related Articles
- EP ID EP11258
- DOI 10.5958/2319-5886.2014.00407.X
- Views 282
- Downloads 12
Effects of aerobic training on FBS, HbA1C, Fructosamine and plasma lipid profile in male with type 2 diabetes
Regular exercise represents an effective strategy to prevent and treat type 2 Diabetes.The present study examined the effects of aerobic exercise on glycemic control and serum lipid profile in men with type 2 diabetes.2...
Sub-neurolytic dose of phenol for popliteal-sciatic nerve block under ultrasound guidance for the relief of ischemic leg pain
Ischemic leg pain is often intractable. Pain relief with conventional analgesics, opioids and non-opioids is often unsatisfactory. It provides only a sub-optimal pain relief in spite of the grievous side effects it caus...
CASE REPORT OF GIANT CONGENITAL MELANOCYTIC NAEVUS
This is a case of giant congenital melanocytic nevus, associated with a single lipoma & multiple satellite lesions. Biopsy report showed skin with groups of nevoid cells extending into underlying fat, intimately associ...
The Pattern to Predict Social Phobia Based On Social Self-Efficacy, Shyness and Coping Style in the Secondary School Students
The aim of this study was to determine predictors of social phobia through studying some social phobias predictors. In this study, shyness, social self-efficacy and coping styles were assessed as predictors of social ph...
A Multifactorial Intervention Based on the NICE-Adjusted Guideline in the Prevention of Delirium in Patients Hospitalized for Cardiac Surgery
Delirium is the most common problem in patients in intensive care units. Prevention of delirium is more important than treatment. The aim of this study is to determine the effect of the NICE-adjusted multifactorial inte...