ROLE OF EARLY CLEAVAGE IN PREDICTING SUCCESS OF INTRA CYTOPLASMIC SPERM INJECTION IN ASSISTED REPRODUCTIVE TECHNOLOGIES
Journal Title: International Journal of Medical Research & Health Sciences (IJMRHS) - Year 2014, Vol 3, Issue 3
Abstract
Aim and Objective: The present study is aimed to carry out the impact of early cleavage over late cleavage in assessing the pregnancy outcome using of Intra Cytoplasmic Sperm Injection (ICSI) in assisted reproductive technologies. Materials and Methods A total of 154 patients enrolled for Intra Cytoplasmic Sperm Injection (ICSI) fulfilling the selection criteria were recruited for the study at a tertiary care assisted reproductive centre. ICSI was performed 3–5 h after oocyte aspiration with the prepared sperm. All embryos were checked for early cleavage at 27 hours post intra cytoplasmic sperm injection. They were divided into two groups. Group IEmbryos which cleaved before 27 hours after Intra Cytoplasmic Sperm Injection (ICSI). Group II- Embryos which cleaved after 27 hours. The pregnancy rates were compared between the two groups. Results: All the 154 patients were analysed. There was no difference in the mean age, duration of ovarian stimulation, number of oocytes retrieved, fertilization, cleavage rates and embryo quality between the two groups. Early cleavage was observed in 98 patients (63.64 %). Late cleavage was observed in 56 patients (36.36%). The clinical pregnancy was confirmed in 59 patients (60.20%) in Group I and 20 patients (35.71%) in Group II which was statistically significant P <0.001. Conclusion: Early cleavage is a strong predictor of embryo quality and can predict ICSI outcome.
Authors and Affiliations
Manjula Gopalakrishnan| Embryologist, Department of Reproductive Medicine, Sri Ramachandra University, Chennai, Corresponding author email: manjuladaniel2000@yahoo.co.in, manjula2000srmc@gmail.com , Sanjeeva Reddy Nellapalli| Professor & Head, Department of Reproductive Medicine, Sri Ramachandra University, Chennai, Muthiah sinvaniah surulimuthu| Embryologist, Kanmani Fertility clinic, Chennai
Keywords
Related Articles
- EP ID EP11258
- DOI 10.5958/2319-5886.2014.00407.X
- Views 276
- Downloads 12
Pathology of Faculty Members’ rank Promotion in Universities and Higher Education Institutions Affiliated to the Ministry of Health and Medical Education of the Islamic Republic of Iran
The success of faculty members of medical sciences universities to promote higher ranks is through long-term evaluation of four educational, research, executive, and cultural performances them. This descriptive-analytic...
REGIONAL FACTORS RELATED WITH THE NUMBER OF AMBULANCE USERS
Introduction: Ambulance use was increasing along with growth population of aged in Japan. The purpose of study paper is to clarify the relationship between the state of healthcare service use as well as regional chara...
CORONARY DOMINANCE IN SOUTH INDIAN POPULATION
Coronary artery anomalies are considered clinically insignificant and known to be associated with other congenital heart defects, myocardial ischemia and reduced life expectancy. Almost all elderly people have at least...
Silhouette of substance abuse amongst an adolescent sample group from urban slums of Guwahati metro, North East India
Globally 320 million young people between ages 15-29 years are dying from alcohol related causes. Child line foundation survey report showed that 13.1% of the people involved in drug and substance abuse in India, are a...
DETECTION OF BIOFILM PRODUCTION IN BLOOD CULTURE ISOLATES OF STAPHYLOCOCCI
Background: Biofilm producing bacteria which are inherently resistant to antibiotics and disinfectants are widely associated with implant associated infections. Staphylococcus is the most commonly associated pathogens w...