Role of extended histological examination in the assessment of local recurrence of the oral cancer
Journal Title: Otolaryngologia Polska - Year 2015, Vol 69, Issue 1
Abstract
IntroductionOral cancer is the second most prevalent head and neck malignancy in Poland. The incidence of these types of cancer is constantly growing. A reason for a treatment failure of the oral cancer is local recurrence. Aim of the study:To find out why the rate of recurrence of the oral cancer is so high despite radical surgical treatment combined with radiochemotherapy. Materials and methods: The study comprised a group of 160 oral cancer patients. 30 patients who showed local recurrence were given an extended histopathological examination in keeping to the guidelines of the Royal College of Pathologists. ResultsIn 9 patients, primary tumours were found to be histologically aggressive as indicated by the proliferation of the vessels, nerves and muscles. In next 9 cases, the cancer infiltrated both the vessels and nerves or the vessels and muscles, and in the 8 other cases, just one of those structures. The tumours which were found to penetrate the vessels, nerves and muscles were also characterised with peri- and intraneural infiltration. The aggressiveness of invasion measured by the extent of damage done to the muscles, vessels and nerves correlated with the depth of invasion from the mucous membrane, the occurrence of embolisms in blood vessels, and a high (score 4) risk assessment as proposed by Margaret Brandwein-Gensler.Conclusion The progression of cancer depends strongly on histopathological features. The incidence of penetration of the vessels, nerves and muscles correlates with aggressiveness of the front of tumour and few other histological features.
Authors and Affiliations
Bartosz Szybiak , Konstanty Korski , Wojciech Golusiński
Keywords
Related Articles
- EP ID EP52579
- DOI -
- Views 114
- Downloads 0
Metallic foreign body in the Neck: Case Report
SUMMARY Penetrating neck injuries constitute 5-10% of all trauma cases. Such injuries are dangerous because of the high risk of injury to the vital structures in the neck and hence demand an immediate surgical exploratio...
Znaczenie badań elektrofizjologicznych w diagnostyce guzów nerwu VIII
SUMMARY The most important for the diagnosis of vestibular schwannoma is MRI tech-nic, which allows assessing its size and shape. The gold diagnostic standard includes also PTA, SD and ABR, nystagmography with calorics a...
Operacje z dostępu Draf III w materiale Kliniki Otolaryngologii WUM
During last decades Draf III procedure gained popularity in treatment of different pathologies of the frontal sinus such as chronic sinusitis or benign tumors. We present a series of 10 patients treated with this procedu...
Ekspresja receptora CD27 na limfocytach T i B w tkance przerosłych migdałków gardłowych u dzieci chorych na wysiękowe zapalenie ucha środkowego
Introduction: Adenoid has particular meaning to develop of immunological response to inflammations in upper respiratory inclusive middle ear. The mining of antigen CD27 on lymphocytes T and B in creation of memory cells...
A new approach to studying the nasal and oral breathing routes
Introduction: Nasal obstruction is often reported by patients. It is a consequence of a subjective feeling of impaired airflow through the nasal cavity. Currently, objective measures of nasal patency rates are very limit...