Role of Filaggrin in Pediatric Allergology
Journal Title: Здоров`я дитини - Year 2013, Vol 2, Issue 45
Abstract
There had been found strong evidence that a violation of the epidermal barrier is a necessary condition for the development of sensitivity to allergens. Study of defects in the filaggrin gene is a major breakthrough in understanding the molecular and genetic mechanisms of atopic and allergic diseases. The study of filaggrin molecules and defects in filaggrin gene is important to consider further strategies for treatment of atopic dermatitis, and ultimately for preventing the development of allergic diseases.
Authors and Affiliations
A. P. Volosovets, S. P. Krivopustov, Ye. V. Pavlik
Keywords
Related Articles
- EP ID EP234434
- DOI -
- Views 71
- Downloads 0
MORPHOfunctional changes of gallbladder and biochemical parametErs of lipid metabolism in children with liver steatosis
Background. The aim of study was to investigate peculiarities of structural and functional disorders of gallbladder in children with non-alcoholic fatty liver disease. Materials and methods. The study was conducted in 51...
Risk Factors and Pathogenesis of Gastrointestinal Food Allergy in Children
The literature review presents modern data on the views on risk factors of the development, etiology and pathogenesis of gastrointestinal food allergy in children. The article details the mechanism of some forms of gastr...
Transient Neonatal Diabetes Associated with Chromosome 6Q24 Imprinting Abnormalities Part 4. Differential Diagnosis and Treatment
The article presents the differential diagnosis of diseases that occur with neonatal hyperglycemia. The common causes of neonatal hypoglycemia, variants of its combination with clinical manifestations from the various or...
Features of Parameters of Glial Protein S100 Amount and the Level of Total Nitric Oxide Metabolites in the Blood of Extremely Preterm Infants with Perinatal Hypoxic Brain Damage
The frequency of low birth-weight children with extremely low and very low birth weight infants over the past decade has remained stable and in the developed world is 5–12 % of the total number of births. Frequency of pe...
Modern Aspects of Training General Practitioners in Higher Medical Education Institutions
This work provides modern aspects of teaching discipline «general practice — family medicine» on the undergraduate stage in higher medical educational institutions of our county in view of the experience gained in the Za...