Role of Flexible Fiberoptic Bronchoscopy in Sputum Smear Negative Pulmonary Tuberculosis Patients Undergoing Treatment Under Revised National Tuberculosis Control Programme (RNTCP)
Journal Title: INTERNATIONAL JOURNAL OF CURRENT RESEARCH IN MEDICAL SCIENCES - Year 2018, Vol 4, Issue 3
Abstract
Background: India is the country with the highest burden of Tuberculosis and accounts for one fourth of the global TB burden. Sputum-negative pulmonary tuberculosis still remains a common problem, more so in immunocompromised patients. The various diagnostic methods which can help in early diagnosis of suspected sputum smear negative pulmonary tuberculosis (SSN-PTB) cases are sputum Fiber optic bronchoscopy which offers an effective investigative tool in sputum smear negative cases, whereby bronchial secretion and washing can be collected from the most likely abnormal site under direct vision. We conducted an observational cross sectional study to assess the diagnostic yield of fiberoptic bronchoscopy in sputum smear negative patients and chest x-ray suggestive of pulmonary tuberculosis. Methods: 50 patients who have Chest x ray findings suggestive of pulmonary tuberculosis but sputum smear is negative for AFB where subjected to bronchoscopy after getting informed consent. Results: Overall diagnostic yield of various bronchoscopic specimens in diagnosing tuberculosis were trans-bronchial lung biopsy (53.8%), broncho-alveolar lavage/washings (46%), bronchial brushing (38%) and post bronchoscopic sputum (24%) in our study. In the present study, bronchoscopy was helpful to establish the diagnosis in 46 out of total 50 cases. 34 (68%) patients had tuberculosis, 8 (16%) had pyogenic infections/pneumonia, 4 (8%) patients were diagnosed with malignancy and the results were inconclusive in 4 (8%) patients. Conclusion: The combination of various modalities during bronchoscopy produced better results than any of the modalities alone as far as diagnostic yield is concerned.
Authors and Affiliations
Naveen Pandhi1 , NC Kajal 2 , Balbir Malhotra2 , Nishanth. P. S3 , Amarendra Kumar Shukla3 , Ashi Singh3 , Vijay Gotwal 3 , N. S. Neki4
Keywords
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- EP ID EP563394
- DOI 10.22192/ijcrms.2018.04.03.016
- Views 130
- Downloads 0
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