Role of Flupirtine as a Preemptive Analgesic in Patients Undergoing Laparoscopic Surgeries
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2017, Vol 5, Issue 4
Abstract
Abstract: Acute postoperative pain after laparoscopic surgery limits the function and mobility of patients in postoperative period.The aim of present study is to study Flupirtine regarding its efficacy as preemptive analgesic in elective laparoscopic surgeries.In this randomized prospective study 100 patients were divided into two groups. Group-F received two capsules of Oral Flupirtine 100 mg each and group- P received two multivitamin capsules(placebo) with sip of water 2 hour before the expected time of induction of anaesthesia. Time for requirement of first dose of rescue analgesic post operatively, VAS score and dose of rescue analgesic used in first 24 hours post operatively were assessed.Group F had lower visual analogue score(VAS) in comparison to P group. Time for requirement of first dose of rescue analgesic in P group was less compared to F group. Consumption of rescue analgesic was less in F group in comparison to P group. Flupirtine as preemptive analgesic produced prolonged postoperative analgesia compared to placebo. Keywords:Flupirtine, preemptive analgesic
Authors and Affiliations
Sumita Mohanty, Rekha Das, SidharthSraban Routray, Abhilash Dash, Sunil Kumar Routray
Keywords
Related Articles
- EP ID EP372207
- DOI -
- Views 75
- Downloads 0
Co-infection with Cryptosporidium, Isospora and Giardia Lamblia in a Patient Living with HIV and AIDS- a Case Report
A thirty nine year old male positive for Human Immunodeficiency Virus and AIDS, was found to be positive for three different opportunistic parasitic infections. Cryptosporidium, Isospora and Giardia lamblia were simultan...
Acute Effect of Breakfast on Cognitive Performance in Young Adults
Abstract: The present study aims to assess the cognitive performance before and after breakfast in healthy young adults (males).This effect may help in understanding the importance of breakfast on academic performance al...
A Study on Incidence of GDM at A Tertiary Care Centre
Abstract: The aim is to find the incidence of GDM using 75-g oral glucose tolerance test (OGTT) as a single-step screening and diagnosing GDM. Antenatal women attending Obstetrics department OP at Government Rajaji hospi...
Acute Oral Toxicity Evaluation and Median Lethal Dose Determination of Ethanolic Extract of Quercusinfectoria galls (Fagaceae) in Experimental Rats
Medicinal plants, either as an extract, pure compound or as a derivative, offer limitless opportunities for the discovery of new drugs. It is popularly believed that medicinal plants are safer than pharmaceuticals becaus...
Surgery for Primary Anterior Mediastinal Tumors: a Report of 71 Cases from a Single Institute
Abstract: The aim of this study was to review the clinical presentations, diagnostic tools adopted, the histological features and the treatment of primary anterior mediastinal tumors.A retrospective analysis of 71 patien...