Role of immunoglobulin E and gastro-esophageal reflux disease in the development of otitis media with effusion
Journal Title: Otolaryngologia Polska - Year 2014, Vol 68, Issue 3
Abstract
Introduction: The role of allergy in chronic otitis media with effusion (OME) is controversial. Aim of the work: To study the role of allergy and gastroesphogeal reflux diseases in the etiology of OME. Materials and methods: It is a prospective study that was done on 43 cases; 30 patients suffer from OME with mean age 6.8 years and 13 control child with mean age 8.3 years. Blood sample were taken from patients and control children for assay of total Immunoglobulin E (IgE) and serum pepsinogen 1 (PG1). Effusion fluid samples were taken from middle ear of the patients during myringotomy and ventilation tube insertion; IgE and PG1 were assayed in the effusion samples. Total IgE and PG1 were assayed by enzyme-linked immunosorbent assay. Results: Our results showed that, there is a correlation between serum IgE and Effusion IgE in the patients group, there is a significant negative correlation between PG1 in the effusion and serum of the studied patients. Conclusion: Allergy is a possible risk factor for the development of OME. The level of PG1in the effusion is one tenth of its level in the serum of the patients.
Authors and Affiliations
Mohammed A. Gomaa, Abdel Karim, Yaser Elsherbeny
Keywords
Related Articles
- EP ID EP52511
- DOI -
- Views 66
- Downloads 0
Poszukiwanie patologii słuchowo-przedsionkowej w celiakii
The aim of the study was looking for the vestibular or/and auditory pathology in patients with celiac disease. The group of 30 cases aged 6–18 (mean: 9,2) were tested. The results were compared with 30 healthy persons ag...
Early complications of Griggs percutaneous tracheotomy in own material
SUMMARY Introduction: The aim of the work was to assess early complications of Griggs percutaneous tracheotomy in the own material. 'al and methods: The study covered 155 patients aged 17-88, including 36 women and 119 m...
„Nie kradnij” znaczy także „nie popełniaj plagiatu”
The article contains essay-like considerations on causes of the phenomenon of scientifi c plagiarism. The paper shows that an excess of the so-called professional codes of ethics effectively stifl es the voice of our con...
Draf III procedures: the ENT Department, Medical University of Warsaw experience
During last decades Draf III procedure gained popularity in treatment of different pathologies of the frontal sinus such as chronic sinusitis or benign tumors. We present a series of 10 patients treated with this procedu...
Results of rehabilitation of voice and speeches after implantation of valve vocal prosthesis at ill after total removal of larynx
Ill applying with extensive infi ltration of new-growth within of larynx will demand radical therapeutic procedure, which is operation completely removals of organ. Aim of work was estimation of voice and speeches ill wi...