Role of Inj. Dexamethasone for prevention of post operative nausea and vomiting in laparoscopic surgeries
Journal Title: Medpulse International Journal of Anesthesiology - Year 2017, Vol 3, Issue 2
Abstract
Aims and Objectives: To study the role of inj. Dexamethasone for early and late Post Operative Nausea and Vomiting in laparoscopic surgeries. And also to record side effects of dexamethasone. Study Design: Prospective, randomized, double blind trail. Material And Methods: Total 80 patients of ASA physical states I and II were randomly allocated to two groups of 40 each. After induction of general anesthesia, Group D received 8 mg/kg Dexamethasone, Group C received normal saline 2 ml. Both the groups were compared on the basis of vomiting up to 6 hrs after conclusion of surgery (Early PONV), and 6 hrs to 24 hrs after surgery (late PONV).Also the side effects i.e. infection at port site, or any bleeding from wound was recorded. Results: Post operative nausea and vomiting up to 6 hrs in Group D was 4 as compared to 6 in Group C. While incidence of late PONV was 8 in Group D Vs 16 in Group C which is statistically significant. No patient in any group had wound infection or bleeding from port site in postoperative period. Conclusion: Inj. Dexamethasone effectively reduces late post operative nausea vomiting, without any added evidence of side effects
Authors and Affiliations
Manohar Mane, Divakar Patil, J Paranjape, Ravikiran Thote
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