Role of Insulin Resistance in Acne Vulgaris: A Hospital Based Observational Study
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 2
Abstract
Background and aim: This study was aimed to assess the role of insulin resistance in acne vulgaris. Materials and method: This was a hospital-based, observational study done on 300outdoor patientswho were clinically diagnosed to have acne.HOMA IR (Homeostatic model assessment for insulin resistance) was calculated for all patients. Results: In our study, out of 300 cases, 154 (51.3%) were females and 146(48.7%) were males. Most of the cases (29.6%) were between 16-20 years of age followed by (20.6%) 21-25 years of age. 72.7% of the patients were students. Out of 300, 54% patients were adopting high glycemic diet.Grade II acne was found in 182 of 60.7%, followed by grade III in 77 (25.7%); grade I in 26(8.7%) and grade IV in 15 (5%) patients.Fasting serum Insulin levels was raised(>20) in 48(16%) females and 38(12.7%) males.HOMA IR level was raised(>2.5) in 86(28.6%) patients out of which 48(55.8%) were females and 38(44.2%) were males. Out of 154 female patients 32 were positive for PCOS. Conclusion: 28.6% patients showed raised HOMA IR which shows that high glycemic diet plays a significant role in insulin resistance acne.
Authors and Affiliations
Arvind Verma, Savita Agrawal, Manisha Nijhawan, Shivi Nijhawan, Rakesh Jhangra, Manmohan Bagri, Anand Sharma, Subhash Bishnoi
Keywords
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- EP ID EP467559
- DOI 10.9790/0853-1802086368.
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