Role of intravenous paracetamol as an adjunct to epidural analgesia in immediate postoperative period in abdominal cancer surgeries
Journal Title: Indian Journal of Clinical Anaesthesia - Year 2018, Vol 5, Issue 1
Abstract
Aims and Objectives: To evaluate analgesic efficacy and side effects of intravenous paracetamol, also assess IV-PCA morphine consumption in patients undertaken abdominal cancer surgery. Materials and Methods: Total 160 ASA grade I and II patients of both the sex, between age 18-70 years were randomly divided in two equal groups to receive either IV paracetamol 1gm or no paracetamol after surgery. Hemodynamic parameters, pain intensity scores, amount of morphine consumption and side effects were recorded. Results: The control group had higher mean heart rate, mean arterial blood pressures, mean respiratory rate than paracetamol group. Pain intensity score was much higher in control group at any time which needed considerably higher dose of rescue analgesic (IV morphine) for pain control than paracetamol group. We found no significant difference statistically in sedation scores in patients using patient controlled analgesia in either group. Side effects were found to be lower in paracetamol group compared to control group but difference was not significant statistically. Conclusion: Paracetamol is safe and effective drug for postoperative analgesia with negligible side effects.
Authors and Affiliations
Navnath K. Sonale, Devanand B. Pawar
Keywords
Related Articles
- EP ID EP472283
- DOI 10.18231/2394-4994.2018.0005
- Views 56
- Downloads 0
Comparison of catheterization of internal jugular vein by ultrasound guided versus landmark approach IN I.C.U. patients
Introduction Central venous line placement is one of the essential procedures in the treatment of critically ill patients admitted in the intensive care unit Central venous catheterization is required not only for provid...
Spinal and Epidural anaesthesia for Caesarean section in severe preeclampsia – a comparative prospective randomized study
Preeclampsia is a multisystem disorder of pregnancy associated with significant maternal, foetal and neonatal morbidity and mortality.
Prognostic applicability of simplified acute physiology score (saps 3) in critically ill adult surgical patients in a tertiary Indian hospital: A preliminary study
Introduction and Aims: Prognostic indices are infrequently practiced in surgical intensive care units (SICU) of Indian tertiary care hospitals to assess the overall outcomes. Simplified Acute Physiology Score 3 (SAPS 3)...
A study of effectiveness of 0.5% bupivacaine for sensory blockade as local anesthesia in epidural and spinal phase
Background: Bupivacaine is a long-acting local anesthetic. Addition of epinephrine is thus rarely required. It blocks initiation and transmission of nerve impulses at the site of application by stabilizing the neuronal m...
Comparison of Oxytocin 3IU Bolus + I.V. Infusion 0f 30IU at the Rate of 125 ml/Hr.(0.125 IU/Min.) and oxytocin I.V. infusion at 0.125 IU/Min only, in maintaining uterine tone and hemodynamic stability in parturient undergoing caesarean delivery
Oxytocin is routinely administered during caesarean delivery to initiate uterine contraction and thus decrease the blood loss from the site of placental attachment. Adverse effects are known to occur after I.V. oxytocin...