Role of ionized calcium in critically ill patients
Journal Title: INTERNATIONAL JOURNAL OF RECENT TRENDS IN SCIENCE AND TECHNOLOGY - Year 2017, Vol 22, Issue 3
Abstract
Background: Ionized calcium (iCa) is the calcium that is present in the blood in a free form and not attached to proteins. It is the physiologically active form of calcium. Abnormalities of ionized calcium concentration are common in critically ill patients and the vast majority of these abnormalities are due to hypocalcemia. Aim and Objective: The aim of the study was to see how ionized calcium values differ in critically ill patients before treatment compared to after treatment, it was done to show the importance of ionized calcium in critically ill patients as one of the marker of effectiveness of the treatment as well as to show how abnormally low values can be fatal. Method: The present study was conducted on 30 patients admitted to the ICU and 10 health check-up patients. Measurement of ionized calcium was done using ABL 800 Basic analyser and the values were correlated with parameters like magnesium, albumin, total calcium, creatinine, whole blood count and platelet count. Results: After analysing the data obtained it was observed that when ionized calcium was very low, the patient was in poor state and the prognosis was bad. After treatment, the ionized calcium levels improved. When ionized calcium was higher than the initial value, the patient was in a good state and the prognosis was good. Conclusion: The findings in the study suggest that ionized calcium can be considered as one of the markers in showing the effectiveness of treatment. In good prognosis the values of ionized calcium are raised while in bad prognosis hypocalcaemia is associated with mortality. A direct measurement of ionized calcium is a must for critically ill patients. Estimation of ionized calcium can be routinely done to check how a patient is responding to treatment.
Authors and Affiliations
S A Chogle, C A Sathe, L Colaco, D D Bharadwaj
Keywords
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