ROLE OF MAGNESIUM AS HYPOGLYCEMIC AGENT IN TYPE 2 DIABETES MELLITUS
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2016, Vol 3, Issue 7
Abstract
INTRODUCTION Magnesium deficiency has been associated with Insulin Resistance (IR) and increased risk for type 2 diabetes in adults. We evaluated the relationship between magnesium and insulin resistance in obese diabetic woman visiting to medical outpatient clinics (OPD). METHODS In this cross-sectional study, a total of fifty diabetic female subjects with age group of 30-60 years, whose body mass index was above 30kg/m2 were studied for 16 months between July 2013 to November 2014 who were attending general medicine OPD were studied. Subjects with endocrine disorders other than diabetes or who were taking multivitamin supplements or corticosteroids were excluded. Blood samples were assessed for Serum magnesium, Fasting blood sugar, Fasting Insulin and HOMA IR was calculated. RESULTS A total of fifty subjects participated in the study. The mean age of the patients was 31.4±7.32 years. We found that 43/50(86%) of these subjects are having insulin resistance as estimated by HOMA IR and 37/50(74%) are having hypomagnesaemia. Serum magnesium was inversely correlated with HOMA-IR (spearman r−0.44, P<0.05). CONCLUSION In our study, we observed that hypomagnesaemia coexists with insulin resistance in obese diabetics with insulin resistance. Caution has to be executed in interpretation of results as our sample is small. Serum magnesium deficiency in obese children may be secondary to decreased dietary magnesium intake
Authors and Affiliations
Rekha Kumari
A STUDY OF PREVALENCE OF HYPOTHYROIDISM IN CHOLELITHIASIS
BACKGROUND For decades, there has been discussion whether thyroid disorders could cause gallstone disease. Gallstone formation is a complex process involving various mechanisms affecting the flow of bile and bile content...
MRI EVALUATION OF EPILEPSY WITH CLINICAL CORRELATION
BACKGROUND Epilepsy is a chronic disorder characterized by a spontaneous tendency for recurrent seizures. An epileptic seizure is a clinical manifestation of abnormal, excessive neuronal activity arising in the grey matt...
ISOBARIC ROPIVACAINE 0.75%, WITH AND WITHOUT INTRATHECAL DEXMEDETOMIDINE AS AN ADJUVANT, IN LOWER LIMB SURGERY- A COMPARISON
BACKGROUND Spinal Anaesthesia is the most common approach which is used for lower limb surgery. Ropivacaine is the preferred compound in comparison of Bupivacaine as firstly it is enantiomer specific which shows less car...
PREVALENCE OF ANAEMIA AMONG CHILDREN AGED 12 YEARS AND YOUNGER IN NORTH EAST INDIA
BACKGROUND AND OBJECTIVE Anaemia is one of the most important public health problem among children. The infants, preschool children, adolescents and pregnant women are at highest risk of nutritional anaemia. The aim of t...
DIABETIC FOOT DISEASE IN KING GEORGE HOSPITAL, VISHAKAPATNAM: A DESCRIPTIVE STUDY ON 100 PATIENTS
Diabetic foot as the leading cause of lower limb amputation is one of the most important complications of diabetes mellitus. Effective treatment and formulation of prevention guidelines for diabetic foot require a thorou...