Role of MDCT in Detection and Characterisation of Focal Liver Lesions
Journal Title: Journal of Clinical and Diagnostic Research - Year 2019, Vol 13, Issue 5
Abstract
ABSTRACT Introduction: Multiphasic Computed Tomography (CT) has become the primary imaging modality for detection and characterisation of focal liver lesions. CT has assumed primary role in evaluating hepatic masses. Aim: To assess the imaging features of focal liver lesions on Multidetector Computed Tomography (MDCT) and its comparative evaluation with histopathological results. Materials and Methods: This cross-sectional study was conducted in the Department of Radiodiagnosis in a tertiary care hospital for a period of 18 months. Adult patients of age group 20-60 years with focal hepatic lesions on abdominal imaging (USG), all patients presenting with deranged liver function or known cases of liver mass lesions were included in the study and Quadriphasic Contrast Enhanced Computed Tomography (CECT) scan was done for them followed by biopsy. All the values for the arterial phase, venous phase, portal phase and delayed phase were recorded and analysed along with the histopathological and biochemical analysis report. Results: As detected by MDCT, out of 84 focal liver lesions, benign focal liver lesions were 72(85.7%) and malignant lesions were 12 (14.3%). The diagnostic accuracy (efficiency) of MDCT was found to be 90.5% with predicted value (95% CI: 84.20-96.75%). For the hepatocellular carcinoma cases, highly significant agreement (p<0.001) was found between MDCT and biopsy techniques. The overall sensitivity, specificity, PPV, NPV and diagnostic accuracy for malignant lesions was found to be 83.3%, 97.2%, 83.3%, 97.2% and 95.2% respectively. Conclusion: This study indicates MDCT to be highly sensitive in classifying the hepatic lesions into clinically relevant categories, making diagnosis and evaluation of lesion. It opens up new possibilities of early detection of liver lesions and its management.
Authors and Affiliations
Shreshtha Jain, Sachin Khanduri, Jigar Kirit Shah, Poonam Yadav, Anvit Krishnam
Keywords
Related Articles
- EP ID EP583340
- DOI 10.7860/JCDR/2019/41303.12857
- Views 85
- Downloads 0
Ultrasound Elastography for Differentiating Benign from Malignant Cervical Lymphadenopathy: Comparison with B-Mode and Color Doppler Findings
Introduction: Elastography is a new technique that aim to assess tissue hardness non-invasively. Recently, it has been used for differentiating benign from malignant lymphadenopathy. Aim: To evaluate the sensitivity and...
Pneumococcal Vaccination among Adults with Respiratory Diseases-Indications, Adherence and Roadblocks
ABSTRACT Introduction: Globally, invasive pneumococcal disease poses a major challenge to the health system and causes significant economic burden. Pneumococcal vaccination is a recommended and well adhered practice amon...
Ectopic Primary Intrathyroidal Thymoma: A Case Report and Review of Literature
Thymomas are rare neoplasms comprising less than 1% of adult cancers. Ectopic thymomas are thought to arise from aberrant thymic tissue displaced during embryologic development and are extremely rare accounting for only...
Evaluation of Myocardial Injury using Standard Diagnostic Tools and Tissue Doppler Imaging in Blunt Trauma Chest
Introduction: Myocardial contusion is an entity in chest trauma which is difficult to diagnose. Current practice relies more on cardiac-specific biochemical markers and standard echocardiography, but no gold standard tes...
Sinus Rhythm in Rheumatic Mitral Stenosis after Balloon Mitral Valvotomy: Is it Feasible?
Introduction: Atrial Fibrillation (AF) is largely present in patients with rheumatic valvular disease, leading to hospitalizations. Aim: We aimed to study the restoration and maintenance of Sinus Rhythm (SR) in rheumatic...