Role of MDCT in diagnosis of lower limb peripheral arteries diseases Ali Basyoni Amin, Haytham Mohamed Nasser, Mohamed Shaker Ghazy Radiology departments, Ain Shams Hospitals.
Journal Title: The Egyptian Journal of Hospital Medicine - Year 2018, Vol 73, Issue 1
Abstract
<strong>Background:</strong> Lower limb peripheral arterial disease (PAD) is a common disease that affects about two hundred million peoples per year. It is the third leading cause of cardiovascular morbidity. We plan to evaluate the diagnostic performance of 64-section computed tomographic (CT) angiography in the assessment of steno-occlusive disease in patients with PAD, with conventional digital subtraction angiography (DSA) as the reference standard. <strong>Aim of study:</strong> is to compare the diagnostic accuracy of multidetector computed tomographic (MDCT) angiography in diagnosis of PAD compared to the DSA as pre-operative evaluation of lower limb peripheral arterial diseases. <strong>Patients and methods</strong>: The study included 20 patients clinically presented with symptomatic PAD from February 2018 to July 2018. The study protocol was approved, and written informed consent was obtained from all patients. The patients underwent CT angiography and subsequent DSA. For stenosis analysis (≥70% stenosis), the arterial bed was divided into 35 segments and evaluated by three readers. Inter observer agreement was determined with generalized κ statistics. Accuracy, sensitivity, specificity, was calculated. Mc Nemar test was used to prove significant differences between CT angiographic and DSA findings. <strong>Results:</strong> A total of 700 arterial segments were evaluated, with excellent agreement between readers (κ ≥ 0.928). On a segmental basis, both sensitivity and specificity for stenosis of 70% or more were at least 96% (386 of 400 segments and 290 of 300 segments, respectively), with an accuracy of 98% (686 of 7oo segments).There was no significant difference between CT angiographic and DSA findings (P = .62–.87). <strong>Conclusion:</strong> The diagnostic performance of 64-section CT angiography is excellent in patients with clinical symptoms of PAD.
Authors and Affiliations
Eman Helal
Keywords
Related Articles
- EP ID EP584423
- DOI 10.12816/ejhm.2018.12066
- Views 87
- Downloads 0
Bilateral Foraminal Stenosis in Patient with Dandy-Walker Malformation: Hiding Pathology
<span>Background: </span><span>Etiologies of hydrocephalus are many and sometimes it can be attributed to be multifactorial in origin. Presence of known cause of hydrocephalus like fourth ventricular pathology may mask f...
Stress Among Medical Students during Simulation Training at King Saud bin Abdulaziz University for Health Sciences
<span>Background: </span><span>Simulation training is increasingly being used as a safe format to instruct students and trainees in different skills and procedures in the field of medicine. In this study, we recorded str...
Epidemiology and Risk Factors of Superficial Fungal Infections in Toukh Primary Health Care Centre
<strong>Background: </strong>Fungal skin infection has become a significant problem. Therefore accurate diagnosis and treatment of the active disease as well as the reduction of the re-infection by continued screening, f...
Assessment of Early Left Ventricular Diastolic Dysfunction in Patients with Metabolic Syndrome by 2D Speckle Tracking Echocardiography
<span>Background: </span><span>Metabolic syndrome predisposes to left ventricular dysfunction and heart failure, early </span> <span>detection of associated subclinical cardiac changes has important diagnostic and progno...
Morpho-Functional Adaptations of the Lingual Epithelium of Two Bird Species Which Have Different Feeding Habits
The dorsal epithelium of the free portion of tongue of laughing dove, Streptopelia senegalensis (granivorous) is characterized by presence of well-developed keratinized epithelium with desquamate parakeratinized one whic...