ROLE OF MULTIPHASE CT IN DIFFERENTIATING PLEOMORPHIC ADENOMA FROM OTHER PAROTID NEOPLASMS
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2018, Vol 5, Issue 39
Abstract
BACKGROUND Pleomorphic adenoma of parotid gland shows mild enhancement immediately after IV contrast injection. This property can be used in differentiating it from other parotid neoplasms. The aim of this study was to register the delayed CT enhancement characteristics of pleomorphic adenoma and to compare these results with the enhancement characteristics of other parotid gland tumors. MATERIALS AND METHODS Twenty pathologically proven parotid gland neoplasms were reviewed on preoperative CT scans. Lesions included two cases of Warthin’s tumors, two cases of squamous cell carcinomas, ten cases of pleomorphic adenomas, two cases of acinic cell carcinoma, three cases of mucoepidermoid cancers and one case of metastasis. CT scans were performed after administration of 140 mL of IV contrast at three serial intervals -first immediately after contrast injection, second after 8 minutes & the last one after 24 minutes. The mean normalized Hounsfield unit (HU) attenuation of these lesions was calculated by drawing ROI around the entire mass. This CT HU was divided by that of the contralateral uninvolved parotid gland without changing the location within parotid gland and size of ROI. RESULTS Progressive homogeneous contrast enhancement was detected with time in all pleomorphic adenomas. Mean enhancement within the lesion was 1.25±0.30 at 8 minutes and 2.33±0.60 at 24 minutes. For non-pleomorphic adenomas, degree and pattern of contrast enhancement between the immediate and delayed CT scans remained same. In our study, A multiphasic CT for pleomorphic adenoma and non-pleomorphic adenoma had high sensitivity, specificity, positive and negative predictive values (98.5% vs. 82.5%, 94.5% vs. 97.5%, 90.7% vs. 94.5%, 100% vs. 91.7% respectively). CONCLUSION Pleomorphic adenomas show delayed CT contrast enhancement with an increase in homogeneity with time. This feature is useful in differentiating it from other parotid neoplasms.
Authors and Affiliations
Mayur N. Patel, Hitesh Kumar K. Rajpura, Rajendra N. Solanki, Hemant Patel
Keywords
Related Articles
- EP ID EP572341
- DOI 10.18410/jebmh/2018/567
- Views 70
- Downloads 0
CALCIUM INDUCED ENHANCED RECOVERY FROM MUSCLE RELAXANTS AFTER REVERSING WITH NEOSTIGMINE AND GLYCOPYRROLATE
BACKGROUND Incomplete recovery from muscle relaxants is a potentially hazardous condition. Calcium ions play a significant role in neuromuscular transmission. This study is to find out whether Ca2+ administration after r...
CLINICAL OUTCOME WITH ADD ON RACECADOTRIL VERSUS STANDARD CARE IN PAEDIATRIC GASTROENTERITIS – OUR EXPERIENCE
BACKGROUND Acute gastroenteritis (AGE) is a diarrheal disease of rapid onset, with an increase in the water content, volume, or frequency of stools and often self-limiting. The WHO recommends ORS as the treatment of choi...
VARIABLE PRESENTATIONS OF ACUTE APPENDICITIS
BACKGROUND Acute appendicitis is the commonest cause of pain in all age groups, which if not diagnosed and treated can lead to perforation and peritonitis. So early diagnosis and prompt treatment can reduce morbidity and...
RETROSPECTIVE STUDY OF MANAGEMENT AND OUTCOME OF CUT THROAT INJURY IN A TERTIARY CARE CENTRE
BACKGROUND Cut throat injuries are potentially devastating type of injuries with associated emotional, physical and financial burden on community and hospital resources. As per definition, cut-throat injuries are incised...
MAGICO-RELIGIOUS BELIEF IN PSYCHOSIS
BACKGROUND Magico-religious beliefs are widely prevalent in India and eastern countries compared to western countries. This causes the patients and their families spending extra ordinary time, money and effort in seeking...