Role of non-HDL cholesterol in type II diabetes mellitus
Journal Title: International Journal of Clinical Biochemistry and Research - Year 2018, Vol 5, Issue 4
Abstract
Introduction Type 2 diabetes mellitus is a widespread global disorder among which India is the one where 13rd of the population suffering from diabetes and majority of them were diagnosed during the complication Diabetic dyslipidemia is the major contributor for the cardiovascular disease Measurement of cholesterol level without HDL total cholesterol minus HDL cholesterol could be a valuable indicator of this risk The atherogenic plasma index AIP reveals the balance between atherosclerotic and protective lipoproteins Log TG HDLc and can also predict cardiovascular risk in patients with type II diabetes mellitus The main aim and objective of the study is to find out the role of Non HDL cholesterol in assessing the cardiovascular risk and also atherogenic index of plasma AIP ascertained as log TGHDLC can been utilized as a massive indicator of atherosclerosis and cardiovascular dangers in type II diabetes mellitus Materials and Methods Casecontrol study included 100 50 men and 50 women patients with newly diagnosed type II DM in the 3265 age group as cases and 100 50 men and 50 women healthy individuals of the same age group without family history Type 2 DM of the general population as controls All samples were studied for fasting blood glucose total cholesterol LDLc HDLc and Triglycerides while nonHDL cholesterol and AIP levels were calculatedResults The present study showed that there was a significant rise in NonHDLc p Conclusion NonHDL cholesterol and AIP can be used as indicators of diabetic dyslipidemia and also be used to predict the risk of cardiac and vascular disease in type 2 DMKeywords NonHDLc Non HDLc cholesterol AIP Atherogenic index of plasma LDLc LDL cholesterol HDLc HDL cholesterol
Authors and Affiliations
Hemanth Kumara D. S, Muralidhara Krishna C. S, H L. Vishwanath
Keywords
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- EP ID EP475450
- DOI 10.18231/2394-6377.2018.0136
- Views 74
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