Role of non-HDL cholesterol in type II diabetes mellitus
Journal Title: International Journal of Clinical Biochemistry and Research - Year 2018, Vol 5, Issue 4
Abstract
Introduction Type 2 diabetes mellitus is a widespread global disorder among which India is the one where 13rd of the population suffering from diabetes and majority of them were diagnosed during the complication Diabetic dyslipidemia is the major contributor for the cardiovascular disease Measurement of cholesterol level without HDL total cholesterol minus HDL cholesterol could be a valuable indicator of this risk The atherogenic plasma index AIP reveals the balance between atherosclerotic and protective lipoproteins Log TG HDLc and can also predict cardiovascular risk in patients with type II diabetes mellitus The main aim and objective of the study is to find out the role of Non HDL cholesterol in assessing the cardiovascular risk and also atherogenic index of plasma AIP ascertained as log TGHDLC can been utilized as a massive indicator of atherosclerosis and cardiovascular dangers in type II diabetes mellitus Materials and Methods Casecontrol study included 100 50 men and 50 women patients with newly diagnosed type II DM in the 3265 age group as cases and 100 50 men and 50 women healthy individuals of the same age group without family history Type 2 DM of the general population as controls All samples were studied for fasting blood glucose total cholesterol LDLc HDLc and Triglycerides while nonHDL cholesterol and AIP levels were calculatedResults The present study showed that there was a significant rise in NonHDLc p Conclusion NonHDL cholesterol and AIP can be used as indicators of diabetic dyslipidemia and also be used to predict the risk of cardiac and vascular disease in type 2 DMKeywords NonHDLc Non HDLc cholesterol AIP Atherogenic index of plasma LDLc LDL cholesterol HDLc HDL cholesterol
Authors and Affiliations
Hemanth Kumara D. S, Muralidhara Krishna C. S, H L. Vishwanath
Keywords
Related Articles
- EP ID EP475450
- DOI 10.18231/2394-6377.2018.0136
- Views 83
- Downloads 0
Study of malondialdehyde and estimation of blood glucose levels in patients with diabetes mellitus with cataract
Increased oxidative stress may contribute to development of complications in diabetes may result from over production of precursors to reactive oxygen radicals and/ or decreased efficiency of inhibitory scavenger systems...
Creatine kinase & lactate dehydrogenase activity in patients with hypothyroidism
Thyroid hormone exerts its action in all tissues and modulates several metabolic activity. Alteration in thyroid levels has a profound effect on skeletal muscle The aim of this study is to study the association of thyroi...
Altered erythrocyte surface electric charge in β- thalassemia: By Alcian Blue Dye binding
Aim: To evaluate erythrocyte surface electric charge in β- thalassemia by using Alcian Blue dye binding. Objective: Estimate the binding of AB dye to Sialic acid on the surface of thalassemia and normal, healthy erythroc...
Study of serum calcidiol level in pregnancy and its association with fetal outcome
Introduction Presently there are no guidelines for routine screening of vitamin D deficiency in antenatal women therefore this study was planned to find the association of maternal vitamin D level with fetal outcomesMate...
Comparative calcium levels in high exposed and low exposed group of lead based battery workers
Introduction: A comparative study of calcium and phosphorus was conducted in high exposed and low exposed groups of lead battery workers to study the effect of lead exposure in these groups as there were very few systema...