Role of NT-Pro BNP Estimation In Patients with Acute Dyspnoea presenting to Emergency Department
Journal Title: GCSMC Journal of Medical Sciences - Year 2018, Vol 7, Issue 2
Abstract
Introduction: Dyspnoea can be defined as an unpleasant or uncomfortable sensation of difficult breathing experienced by an individual. The differential diagnosis includes acute heart failure (AHF), acute coronary syndrome (ACS) and pulmonary embolism (PE) as the main diseases to be excluded for their potential acute severity and mortality. NT-pro BNP is a sensitive and specific marker of ventricular dysfunction. Methods: Observational cross sectional study was done from October 2016 to October 2017 with 70 patients of acute dyspnoea presenting to emergency department. An automated immuno-analytical test for NT-pro BNP was carried out. Data was analyzed using appropriate statistical tests. Observation: Out of 70 cases of breathlessness, 48 patients were diagnosed with cardiovascular disease, 17 had Respiratory disease and 5 were of other causes (non respiratory, non cardiac). In Cardiovascular causes of breathlessness (n=48) the mean NT-pro BNP level was 2234 pg/ml, and in Non cardiovascular causes of breathlessness (n=22) the mean NT-pro BNP level was 677 pg/ml. Thus, there was a significant difference in the levels of mean NT-pro BNP. Conclusion: The statistically significant difference was observed when plasma NT-pro BNP levels of cardiovascular disease were compared to non cardiovascular disease (in respiratory causes levels were significantly lower) .Thus it supports the ability of NT pro BNP to provide specific information about the cardiac involvement in acute dyspnoea.
Authors and Affiliations
Chirag J Patel, Vidur V Joshi, Utsav Parikh, Binit N Jhaveri
Keywords
Related Articles
- EP ID EP541087
- DOI -
- Views 67
- Downloads 0
A study on Assessment of Knowledge and Attitude towards First Aid in Road Traffic Accidents among College Students of Ahmedabad city, India
Introduction: Fatalities and injuries resulting from road traffic accidents (RTA) are a major and growing public health concern in India. The knowledge of first aid amongst medical students and general public has always...
A Case of Glioblastoma Multiforme in a Known Case of Breast Carcinoma
Glioblastoma multiforme, also known as grade IV astrocytoma, is a fast growing, aggressive type of central nervous system tumor that forms on the supportive tissue of brain. These tumors contain various cell types, hence...
A Cross Sectional Study to Assess the Non-Adherence to Anti-Tuberculosis Treatment and Determinant Factors among Patients with Pulmonary Tuberculosis
Aims: Method: Results: Conclusion: Due to non-adherence of tuberculosis (TB) patients to treatment, complications may arise and if remaining infectious, these patients may infect other people with TB. To obtain informati...
Outcome of Only Posterior Approach in Acetabular Fractures Involving Both Columns
Objective: Clinical outcome in patients with acetabular fractures involving both columns was done in civil hospital, Ahmedabad, aiming to evaluate the efficacy of posterior approach and its radiological and functional ou...
Incidence of Internal Mammary Nodes in Locally Advanced Breast Cancer and Its Prognostic Significance
Objective: (1) To determine the incidence of internal mammary nodal disease on computed tomography (CT) in patients with locally advanced breast cancer (LABC). (2)To determine the prognostic significance of internal mamm...