Role of ormeloxifene in AUB/HMB
Journal Title: Indian Journal of Obstetrics and Gynecology Research - Year 2018, Vol 5, Issue 3
Abstract
Introduction Heavy menstrual blood loss is defined as 80 ml of blood loss during menstruation Abnormal uterine bleeding is abnormal menstruation as regards volume regularity frequency and duration of bleedingMaterials and Methods A total of 100 patients of age group 2545 years were included in this study Patients were thoroughly investigated before inclusion Exclusion criteria were any women with fibroid adenomyosis endometrial hyperplasia breast cancer and coagulopathy Patients were thoroughly investigated before therapy Ormeloxifene was administered orally 60mg twice a week for 3 months followed by 60mg once a week for a monthResults Amenorrhoea was 33 at 3 months follow up which is increased further to 42 at 4 months follow up Similarly 44 women had scanty flow at the end of 4 months treatment Comparison of clinical characteristics shows reduction in duration of menstrual blood loss and rise in haemoglobin from 72 to 9 gmdl which is along with oral iron supplementation Passage of blood also reduced considerably although 7 74 women did not show good responseConclusion The study concluded that ormeloxifene is a good option as it is cheap has twice weekly schedule few side effects and efficacious in reducing the menstrual blood lossKeywords Heavy menstrual blood loss Abnormal uterine bleeding Fibroid Adenomyosis Ormeloxifene
Authors and Affiliations
Uma Pandey
Keywords
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- EP ID EP475145
- DOI 10.18231/2394-2754.2018.0090
- Views 77
- Downloads 0
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