Role of platelet rich plasma in patients of osteoarthritis knee-a prospective study
Journal Title: Indian Journal of Orthopaedics Surgery - Year 2017, Vol 3, Issue 2
Abstract
Introduction: In the present study, we evaluated the effects of 2 courses of PRP injections with 3 weeks interval, on patient's quality of life and functional ability. Materials and Method: It was a prospective study carried out on 55 patients (14 males & 41 females) in the Department of Orthopedics’, Era’s Lucknow Medical College, Lucknow, and Uttar Pradesh from Sep 2015 to March 2016. Age >40 years, Knee arthralgia (>3 months) and Radiologic evidence of articular damage (grades 1-3 of Kellgren-Lawrence scale) based on knee Osteoarthritis criteria of American College of Rheumatology were enrolled in our study. Two intra-articular injections of Platelet Rich Plasma (PRP) at 3 weeks interval was given and patient was regularly followed up after 3rd week, 6th week, 3 months & 6 months of the 1st injection Results: Mean scores of all WOMAC parameters improved significantly compared to before treatment. Each Parameter of the WOMAC Score was compared with baseline score at each follow-up. Reduction in the mean pain, mean physical function and mean total womac scores from base line scores were observed during the course of 1st (3 weeks) &2nd (6 weeks) follow-ups then after marginal increase in scores were reported during 3rd (3 months) and 4th (6 months)follow ups but difference in mean of all scores were significant with the respective base line scores. Conclusion: The results of our study showed that intra-articular knee injections of Autologous Platelet Rich Plasma (PRP) are effective in reducing joint pain, stiffness and improve knee functions in early knee Osteoarthritis.
Authors and Affiliations
Farid Mohammed, Varun Aggarwa, Sudhir S Kushwaha, Amit Verma, Yasir Ali Khan
Keywords
Related Articles
- EP ID EP293877
- DOI 10.18231/2395-1362.2017.0033
- Views 99
- Downloads 0
A prospective study of functional outcome of treatment of supracondylar fracture of femur by locking compression plate
Aim To evaluate the functional outcome of supracondylar femur fracture treated by locking compression plateMaterials and Methods Our study consists of 20 cases of supracondylar femur fracture operated at Sanjay Gandhi in...
Evaluation of Hybrid External Fixator for Tibial Plateau Fractures: A Prospective Study
Background: Tibial plateau fracture is one of the common injuries encountered in our daily clinical practice. The goals of management of these peri-articular fractures are restoration of joint congruity by anatomic reduc...
Atypical presentation of Gout masquerading as a Soft tissue Sarcoma
monosodium urate crystals within and around the joints. Peri articular nodules are a challenge to both clinicians and diagnosticians especially if the nodules are large. Case presentation: A 34 year old male patient pres...
Study on effectiveness of retrograde nailing with long intramedullary supracondylar nail for shaft and supracondylar fractures of femur
Introduction Due to modern lifestyle changes the incidence of distal femur fractures has risen and more so in association with shaft fractures of femur because of fast world and high velocity trauma occurring in road tra...
Shaft humerus fractures treated with interlocking nails vs. locking compression plates; a comparative study
haft humerus fractures account for approximately 2 to 3 % of all fractures and are commonly encountered in clinical practice. Many can be managed conservatively and those that are operated can be treated by either platin...