Role of Prophylactic Antibiotics in Open Mesh Inguinal Hernioplasty: A Prospective Study
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2018, Vol 6, Issue 9
Abstract
Background: Surgical site infection is the most frequent complication in inguinal hernioplasty. Although there is no controversy in the use of prophylactic antibiotics in clean-contaminated, contaminated and dirty wounds in other type of surgeries, there is controversy surrounding the use of prophylactic antibiotics in clean wounds like Lichtenstein mesh hernioplasty. Aims and Objectives: The aim of the study was to determine the effectiveness of prophylactic antibiotics on the prevention of post-operative wound infection in open mesh inguinal hernioplasty. Materials and Methods: This single-blinded randomized controlled trial was conducted at the Department of General Surgery in Nil Ratan Sirkar Medical College and Hospital, Kolkata among patients requiring mesh inguinal hernioplasty. Among the case group, there were 50 patients who were administered antibiotic prophylactically, and among 50 controls, placebo was given before the surgery. Patient record sheet was used to enter the details of each patient. Results: It was found that the adjusted odds ratio came out to be 0.65 with a confidence interval of 0.565–0.95. This means that the odds of having wound infection postoperatively were 0.65 times lower among cases as compared to controls. Statistically, the difference was found to be significant with P < 0.05. Conclusion: Antibiotic coverage before open mesh hernioplasty incurs protective effect against post-surgical wound infection.
Authors and Affiliations
Debasis Ray, Abhishek Bhaumik, Sudeb Saha
Keywords
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