Role of Subareolar Injection of Methylene Blue in Carcinoma Breast
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2017, Vol 5, Issue 2
Abstract
Introduction: Carcinoma breast is the most common disease of adult females and is the leading cause of the death in their middle age. Self-awareness about breast cancer has increased and diagnosing breast cancer in an early stage is possible by the modern screening methods. The axillary lymph node status is the most important prognostic indicator for carcinoma breast. The procedure sentinel lymph node (SLN) dissection provides the operating surgeon with information to do or not to do an axillary dissection. Methylene blue dye was used in this study because of its easy availability, less expensive, safety, and its effectiveness. Aim: The aim of this study was to study the uptake of blue dye in SLN following subareolar injection, the presence of lymph node metastasis among early breast cancer patients, the incidence of skip metastasis among these early carcinoma breast cancer patients. Materials and Methods: All carcinoma breast patients with tumor size <5 cm and with clinically non-palpable nodes were included in this study. Fine-needle aspiration cytology was done in all the cases for the diagnosis of carcinoma breast. They were subjected to injection of methylene blue dye in the subaerolar region to identify sentinel node positivity. Results: The results shows that the simplifi ed technique of identifying the sentinel nodes by using subareolar injection of methylene blue has suffi ciently high technique success rate of 93.3%, methylene blue dye positive SLN were observed in 56 patients (93.3%), but histopathological tumour positive was in 85% and negative in 9 patients accounting for 15% of the total. Sentinel node positive patients also had the positivity of the other axillary node while negative patients had negativity of other axillary node. Conclusion: Our results show that the simplifi ed technique of identifying sentinel nodes by using subareolar methylene blue has suffi ciently high identifi cation rate of 93.3%. Out of 60 patients, SLN was successfully identifi ed in 56 patients. The study showed that high sensitivity of SLNB in this study is 85%.
Authors and Affiliations
S Bethsy Priscilla, V Ponmuthu, P S Sony, Heber Anandan
Keywords
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