Role of vaginal wash prolactin, lactate, and ceruloplasmin in diagnosis of premature rupture of membrane
Journal Title: The New Indian Journal of OBGYN - Year 2016, Vol 3, Issue 1
Abstract
Objectives: To assessing the effectiveness of prolactin, lactate, and ceruloplasmin in vaginal-washing fluid as diagnostic non-invasive markers of premature rupture of membrane. Methods: Eighty pregnant women presented with PROM were randomly selected; speculum test, collection of samples and nitrazine paper test were done .Vaginal washing fluid samples were examined for prolactin, ceruloplasmin and lactate \levels by enzyme-linked immunosorbent assay (ELISA). Results: Measurement of vaginal wash Lactate levels is more sensitive than both Prolactin and Ceruloplasmin. While the specificity of both Prolactin and Ceruloplasmin in vaginal wash are the same and higher than that of Lactate. Conclusion: Measurement of vaginal wash Prolactin, Lactate and Ceruloplasmin with ELISA method is a reliable, and non-invasive test for diagnosis of PROM.
Authors and Affiliations
Eman Ali Abd El Fattah, Tarek Abd El Zaher Karkour, Rasha Nasrat, Khalil M M
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