ROLES OF ANTHROPOMETRIC VARIATIONS AND SERUM HORMONAL (PROLACTIN AND ESTRADIOL) LEVELS ON THE INITIATION OF PRECOCIOUS PUBERTY
Journal Title: European Journal of Pharmaceutical and Medical Research - Year 2019, Vol 6, Issue 5
Abstract
ABSTRACT Aims: The aim of the present study is to evaluate and compare prolactin and estradiol levels of selected male and female subjects within each sex group; as well as to determine subjects who may be potential candidates for precocious puberty based on their ages and hormonal levels of prolactin and estradiol. Study Design: The study sample population included 177 healthy male and female subjects whose blood samples were taken and clinically assayed for prolactin and estradiol by the ELISA kit technique. Methodology: The subjects’ and control’s quantitative values were derived automatically using a 4-Parameter Logistics curve fit of the micro plate reader and subsequently statistically analyzed using One way analysis of variance (ANOVA), Student t-test and Pearson Correlation. Results: Results pointed out that five of the female subjects had very high levels of prolactin, six female subjects had very high level of estradiol, while one male had high level of prolactin—these were adjudged candidates for precocious puberty. Conclusion: An important discovery in this work is the observed decrease in levels of prolactin from age 6 to 10 years in both sexes. It was confirmed that the females have statistically significant higher height, weight, prolactin and estradiol than their male counterparts. Proper prolactin and estradiol hormonal levels in children control many bodily functions including growth and secondary characteristics associated with puberty.
Authors and Affiliations
Dr. Akinluwade K. J.
Keywords
Related Articles
- EP ID EP673255
- DOI -
- Views 134
- Downloads 0
DIFFERENTIAL DIAGNOSTICS OF BENIGN CYSTIC FORMATIONS OF THE BONES OF THE UPPER AND LOWER LIMBS
The article presents the clinical and radiological features of benign bone tumors and tumor-like conditions. The study was conducted on 51 patients with various benign cystic masses of the bones. Specific clinical and ra...
EFFECTS OF GESTATIONAL EXPOSURE TO 2, 4-DICHLOROPHENOYACETIC ACID ON EMBRYOTOXICITY AND FETOTOXICITY IN FEMALE WISTAR RATS
2,4- dichlorophenoxyacetic acid (2,4-D), a plant growth regulator, has been used worldwide as an herbicide. It has been shown to produce a wide range of adverse effects from embryotoxicity and teratogenicity to neurotoxi...
MICROWAVE- ASSISTED SYNTHESIS OF NOVEL CHALCONE DERIVATIVES AND STUDYING OF SOME OF THEIR ANTIMICROBIAL ACTIVITIES
A novel approach for the synthesis of a series of chalcones (3a-f) by the reaction of acetophenones (1a-c) with different aromatic aldehydes (2a-c) as well as barbituric acid (1d) with terphthalaldehyde (2d) under therma...
EXPERIMENTAL STUDY ON SWISS WHITE MICE TO EVALUATE THE ANTIANXIETY EFFECT OF COMMON WILD FIG EXTRACT (FICUS THONNINGII)
Since prehistoric times, man has relied on herbal plants as source of medicine in curing various ailments. This study was carried out to assess the anti- anxiety-like effect of the ethanol extract of Wild fig (Ficus thon...
DETECTION OF COMMUNITY-ACQUIRED AND EXTENDED SPECTRUM BETA LACTAMASE-PRODUCING UROPATHOGENS IN A SUB-URBAN COMMUNITY IN RIVERS STATE, NIGERIA.
Extended-spectrum β-lactamase-producing (ESBLs) organisms are a major challenge today in hospital and community-acquired infections. These plasmid-mediated enzymes hydrolyze extended spectrum Cephalosporins like Ceftazid...