Safety and efficiency in use of dexmedetomidine during stereotactic biopsy
Journal Title: Annales Academiae Medicae Silesiensis - Year 2014, Vol 68, Issue 5
Abstract
INTRODUCTION Dexmedetomidine (DEX) is an agonist of the alfa-2 adrenergic receptor. It possesses unique sedative properties without depression of the cardiovascular or respiratory system. The aim of this work was to evaluate the efficiency and safety of using dex in stereotactic biopsy. MATERIALS AND METHODS 24 patients qualified for stereotactic biopsy were divided into 2 groups: DEX (n = 12) and KON (n = 12). In DEX, 0.5 μg/kg/h dex has been used. In KON there was no sedation used. Intraoperative changes in the systolic blood pressure (SBP) and heart rate (HR) values were compared in both groups. The sedation level was estimated on the OAA/S scale. RESULTS In DEX, the intraoperative SBP value was significantly lower than in the KON group. No hypertension incidence in DEX was observed. Dex provided patient comfort. CONCLUSION Sedation with the usage of dex increases the comfort and safety of patients during stereotactic biopsy.
Authors and Affiliations
Izabela Duda, Stanisław Kwiek, Konstancja Grzybowska, Damian Kocur
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