Safety Comparison of Cisatracurium And Atracurium In Patients Undergoing General Anaesthesia
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 3
Abstract
Non-depolarizing neuromuscular blocking agents like cisatracurium and atracurium differ in pharmacokinetic and pharmacodynamics parameters.Aim: To evaluate the safety profile and differences between cisatracurium and atracurium, widely used in adult patients for general anaesthesia. Materials And Methods: Adverse drug reactions (ADR) monitoringwere performed. Regardless of the type of surgery, 80 patients were randomly divided into two equal groups to receive either cisatracurium or atracurium for general anaesthesiaat Rajendra institute of Medical Science, Ranchi, Jharkhand, India during Feb 2017 to Nov 2017. Results:There was no statistical difference in the ADR prevalence in both groups. The numbers of ADR within atracurium group was higher than cisatracurium group, but this distinction was not statistically significant. Conclusions:According to our study atracurium and cisatracurium hadsimilar safety profile. In hemodynamic unstablepatients the cisatracurium was the appropriate choice.
Authors and Affiliations
Manisha Bhagat, Ekramul Haque, Avinash Mishra
Keywords
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- EP ID EP369645
- DOI 10.9790/0853-1703105152.
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