Safety Comparison of Cisatracurium And Atracurium In Patients Undergoing General Anaesthesia
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 3
Abstract
Non-depolarizing neuromuscular blocking agents like cisatracurium and atracurium differ in pharmacokinetic and pharmacodynamics parameters.Aim: To evaluate the safety profile and differences between cisatracurium and atracurium, widely used in adult patients for general anaesthesia. Materials And Methods: Adverse drug reactions (ADR) monitoringwere performed. Regardless of the type of surgery, 80 patients were randomly divided into two equal groups to receive either cisatracurium or atracurium for general anaesthesiaat Rajendra institute of Medical Science, Ranchi, Jharkhand, India during Feb 2017 to Nov 2017. Results:There was no statistical difference in the ADR prevalence in both groups. The numbers of ADR within atracurium group was higher than cisatracurium group, but this distinction was not statistically significant. Conclusions:According to our study atracurium and cisatracurium hadsimilar safety profile. In hemodynamic unstablepatients the cisatracurium was the appropriate choice.
Authors and Affiliations
Manisha Bhagat, Ekramul Haque, Avinash Mishra
Keywords
Related Articles
- EP ID EP369645
- DOI 10.9790/0853-1703105152.
- Views 79
- Downloads 0
A Study on Fissural Anatomy of lungs in Adult Human Cadavers – Its Clinical Importance
The lungs are essential organs of respiration and are situated in the thoracic cavity on either side of the mediastinum. The arrangement of lung tissue into lobes by fissures facilitates the movements of the lobes in rel...
TP53 Gene Alterations and P53 Protein Accumulation in Human Esophageal Cancer in Khartoum State, Sudan.
TP53 gene alterations were screened in 50 formalin fixed paraffin embedded (FFPE) human esophageal cancer (EC) specimens comprising 43 squamous cell carcinoma (SCC) and 7 adenocarcinoma (AC) using immunohistochemistry (I...
Patch graft following perforation in Terrien’s Marginal degeneration
PURPOSE: To report a case of patch graft performed for corneal perforation in a patient with Terrien’s marginal degeneration. METHOD: A young woman presented with sudden painless loss of vision following a trivial trauma...
MRI Contrast Agents: Developments, Challenges, and Future Trends
Contrast agents in medicine are chemical materials used to improve tissue and fluid contrast in the body during medical imaging. It is mainly used in improving the visibility of blood vessels and the gastrointestinal tra...
Laser In Endodontics-A Review Article
Lasers were introduced into the field of clinical dentistry with the hope of overcoming some of the drawbacks posed by the conventional methods of dental procedures. Since its first experiment for dental application in t...