Safety Comparison of Cisatracurium And Atracurium In Patients Undergoing General Anaesthesia
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 3
Abstract
Non-depolarizing neuromuscular blocking agents like cisatracurium and atracurium differ in pharmacokinetic and pharmacodynamics parameters.Aim: To evaluate the safety profile and differences between cisatracurium and atracurium, widely used in adult patients for general anaesthesia. Materials And Methods: Adverse drug reactions (ADR) monitoringwere performed. Regardless of the type of surgery, 80 patients were randomly divided into two equal groups to receive either cisatracurium or atracurium for general anaesthesiaat Rajendra institute of Medical Science, Ranchi, Jharkhand, India during Feb 2017 to Nov 2017. Results:There was no statistical difference in the ADR prevalence in both groups. The numbers of ADR within atracurium group was higher than cisatracurium group, but this distinction was not statistically significant. Conclusions:According to our study atracurium and cisatracurium hadsimilar safety profile. In hemodynamic unstablepatients the cisatracurium was the appropriate choice.
Authors and Affiliations
Manisha Bhagat, Ekramul Haque, Avinash Mishra
Keywords
Related Articles
- EP ID EP369645
- DOI 10.9790/0853-1703105152.
- Views 71
- Downloads 0
Review of cases involving forensic odontology and its relevance in world statistics: an original study
Forensic odontology usually involves the cooperation & coordination of law enforcement officials, forensic pathologists, forensic odontologists, forensic anthropologists, serologists, criminalistics, & other specialists....
Incidence of Head & Neck Cancers in Western India: A Cancer Center Based Retrospective Analysis
An audit of head and neck cancer cases is a need based study to find its incidence as compared to other total body malignancies. Material and Methods: This is an Institutional retrospective analysis which was done at cur...
A Study of Lateral Nasal Wall: Anatomical Variants,Radiological And Endoscopic Appearance And Role in Symptomatology in Chronic Rhinosinusitis
It is assumed that the anatomical variations of lateral wall of nose contribute to various disease symptoms by blocking normal sinus drainage.This prospective study was conducted on hundred patients suffering from chroni...
A Clinical Study on Surgical Management of Primary Varicose Veins
The aim of study is to study the clinical presentations, surgical management and its outcome and complications associated with varicose veins in lower limbs. Patients and methods:This randomized prospective study include...
Study of Pattern of Thyroid Dysfunction in Patients with Type 2 Diabetes Mellitus in a Rural Hospital in Karnataka
Background and Objectives: Thyroid dysfunction is known to occur in patients with Type 1 DM, It is due to autoimmunity. The prevalence of thyroid dysfunction in patients with Type 2 DM varies between 10% - 31%. Subclinic...