Salivary and Serum 8-Hydroxydeoxyguanosine Level in Simulated Microgravity
Journal Title: Macedonian Journal of Medical Sciences (MJMS) - Year 2010, Vol 3, Issue 4
Abstract
Background. Microgravity is associated with an increased of peroxidative. The effect is more pronounced after long duration space flight and can even last for several weeks after landing. Aim. To determine the influence of a simulated microgravity on antioxidant status of the human body. Material and Methods. 10 healthy volunteers were studied in condition before, during, and just after the simulated microgravity of -6 head –down –tilt (HDT) bed rest for 10 days. We measured the salivary and serum 8-hydroxydeoxyguanosine before, during and recovery of HDT. Results. The 8-hydroxydeoxyguanosine showed significant increase in simulating microgravity. Conclusion. The data provides evidence that oxidative stress is among critical nutritional concerns for long duration space travellers.
Authors and Affiliations
Balwant Rai, BDS, MS, PG| Oral Imaging Centre, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Catholic University Leuven, Leuven, Belgium, Jasdeep Kaur, BDS, SC-ADA| Forensic Odontology Section, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Catholic University Leuven, Leuven, Belgium, R. JainMDS| Jain Dental Clinic, New Delhi, India
Keywords
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- EP ID EP8770
- DOI 10.3889/MJMS.1857-5773.2010.0121
- Views 333
- Downloads 16
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