Sclerosing Angiomatoid Nodular Transformation of the Spleen (SANT): CT and MR Imaging Features of Five Cases with Pathological Correlation
Journal Title: International Journal of Radiology and Radiation Oncology - Year 2016, Vol 2, Issue 1
Abstract
Objective: To describe imaging features of sclerosing angiomatoid nodular transformation (SANT) with pathologic correlation. Methods: Imaging findings of five cases of SANT were retrospectively analyzed and compared with pathological manifestations. Results: All the five cases of SANT were solitary and round masses with maximum diameter ranged from 3 cm to 9 cm. In ultrasound, all the lesions were well circumscribed with one of hypoecho and four of hyperecho with posterior enhancement. Two masses were of hypoattenuation and one was of isoattenuation at pre-contrast CT scanning. At MRI, the two masses appeared isointensity on T1 weighted images, and hypointense nodules with diffuse signal void spots on T2 weighted images. After intravenous contrast materials, all the five masses showed peripheral circle enhancement at the hepatic arterial phase. The enhanced circle persisted and radial enhanced lines occured in three masses and progressive filling in 2 masses at the portal vein phase. At the delay phase, progressive enhancement resulted in two isodensity masses and one hypoattenuation mass with radial enhanced lines at CT, and one obvious hyperintensity mass with central hypointensty scar and one spoke –like appearance enhancement at MR images. The progressive enhancement and hypointensity at T2 weighted MR images were coresponded to abundent fibrous stroma at pathological examinations, while the signal void might result from hemosiderin in the angiomatoid nodules.
Authors and Affiliations
Yuan Jialin, Gong Jingshan
Keywords
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- EP ID EP541265
- DOI 10.17352/ijrro.000018
- Views 50
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Sclerosing Angiomatoid Nodular Transformation of the Spleen (SANT): CT and MR Imaging Features of Five Cases with Pathological Correlation
Objective: To describe imaging features of sclerosing angiomatoid nodular transformation (SANT) with pathologic correlation. Methods: Imaging findings of five cases of SANT were retrospectively analyzed and compared with...