Scoring over Invasive Candidiasis with Candida score
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 11
Abstract
Introduction: Invasive Fungal Infection (IFI) is a critical event in clinical scenario, and Invasive Candidiasis is chief among them, accounting for 70-90% of all IFIs. In 2006, Candida score was developed to predict this life-threating infection . This study makes a similar attempt to identify invasive candidiasis and measure the candida score in the present scenario of a tertiary care hospital, as well as to detect the prevalence of Candida albicansand non-albicansspecies. Materials and methods: This study was undertaken on patients admitted in Intensive care unit of a tertiary medical care hospital. Specimens obtained from different sites were taken to laboratory to culture in Blood agar media If there was growth in Blood agar – Gram staining was done and if Candida was found, it was subcultured in Chromogenic agar plates to identify species. Result: Out of 129 samples, 11 were positive for Candida (8.49%). Out of 11 Candida isolates, only one was Candida albicans, others being non-albicans Candida. Most of them were Candida krusei. Discussion: None of the cases touched the Candida score of 2.5, a predictor of invasive candidiasis. This was a great finding in itself, and was in stark contrast with findings from many institutions. However, our findings also collaborated with them in that maximum clinical isolates were non-albicans type. But here maximum isolates were C. krusei, although most clinical isolates are reported to be C. tropicalis from Asian subcontinents including India, and C. glabrata from Western countries.
Authors and Affiliations
DrBaishali Chakraborty, DrDibyendu Banerjee, DrAnkit Chakraborty, DrBanya Chakraborty
Keywords
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- DOI 10.9790/0853-1711095861.
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