Screening of kojic acid antimicrobial activity against skin pathogens
Journal Title: International Journal of Life Science - Year 2018, Vol 6, Issue 3
Abstract
The antibacterial and antifungal activity of kojic acid was evaluated against medically important skin pathogens. Tube Dilution Assay was used for analyzing of kojic acid minimum inhibitory concentrations (MIC), it was varied from 64 g/ml to 128 g/ml. There was no bacterial growth was appeared at MIC 64 g/ml. Kojic acid inhibited the Trychophyton rubrum MTCC296 and Candidus albicans MTCC3018 growth at MIC 128 g/ml. Disc diffusion method was chosen to elucidate the antimicrobial activity of the kojic acid. Kojic acid inhibitory zone observed was 17 mm, 14 mm, 12 mm and 9 mm, respectively against Pseudomonas aeruginosa MTCC1688, Trychophyton rubrum MTCC296, Streptococcus pyogenes MTCC1924, Candidus albicans MTCC3018, respectively.
Authors and Affiliations
Ranjit Kumar C, Jayalakshmi S
Keywords
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