Screening of lactic acid bacteria with immune modulating property, and the production of lactic acid bacteria mediated fermented soymilk
Journal Title: National Journal of Physiology, Pharmacy and Pharmacology - Year 2017, Vol 7, Issue 12
Abstract
Background: Lactic acid bacteria (LAB) are reported to have immune activating property. The genetically modified LAB strains producing interleukin (IL) -10 were under consideration for the treatment of inflammatory bowel diseases (IBD). Soybean is rich in necessary nutrients, and the fermented soybean products are known for its health benefits. Aims and Objectives: The current study was aimed to screen LAB with the immune activating property, and production and evaluation of LAB mediated fermented soymilk product. Materials and Methods: Screening of LAB from the fermented foods collected in Chiang Mai. To select a potent LAB strain, the LAB isolates were scrutinized for acid tolerant, bile tolerant, growth rate, antimicrobial ability, adhesion property, and induction of IL-10 production. The physical properties of fermented soymilk (FSM) were evaluated, and in vitro activation of IL-10 by FSM was assessed using Caco-2 cell line. Results: About 742 LAB strains were isolated from 335 fermented food samples. Based on the tested properties, LAB33 was selected as a potent LAB strain, and used for the fermentation of soymilk for 30 days. The LAB33 FSM was superior in quality regarding probiotic nature and microbiological safety. Conclusion: The results of the study suggested that LAB33 is the potent probiotic strain for the production of soymilk-based fermented functional food supplements for the betterment of IBD patients. Further, strain identification is required to register the strain in a public repository, and sustainable utilization for the benefit of mankind.
Authors and Affiliations
Sasithorn Sirilun, Chaiyavat Chaiyasut, Periyanaina Kesika, Sartjin Peerajan, Bhagavathi Sundaram Sivamaruthi
Keywords
Related Articles
- EP ID EP292738
- DOI 10.5455/njppp.2017.7.0933926092017
- Views 87
- Downloads 0
Effect of levamisole administration on immunogenic and protective capacity of Brucella abortus RB51
Background: Brucella abortus strain RB51 is a rough strain that was derived after multiple passages of virulent strain 2308. Levamisole, a potent anthelmintic that is widely used in veterinary medicine, is also known as...
Brainstem evoked auditory response in preterm and full-term infants
Background: The survival of preterm infants has increased substantially over last few decades because of improvements in obstetric and neonatal care. However, the newborn experience many perinatal complica...
Evaluation of cardiovascular autonomic reactivity by cold pressor test in thyroid dysfunction in adults: A prospective case-control study
Background:Changes, in thyroid status, have pronounced effects on cardiovascular system reflecting autonomic dysfunction and increased morbidity. Exact interaction between autonomic nervous activity and thyroid hormones...
Randomized prospective double-blind comparative clinical study of ebastine and its combined preparation of montelukast in persistent allergic rhinitis
Background: Antiallergic drugs are widely prescribed in allergic rhinitis (AR). Antihistamines and antileukotrienes are effective only in providing symptomatic relief of allergic symptoms, often used as fixed dose combin...
Lifestyle risk factors for coronary artery disease among young male patients of urban and rural Dakshina Kannada - A cross-sectional study
Background: There has been an increase in morbidity and mortality due to coronary artery disease (CAD) in developing countries due to multiple risk factors. India’s concern is not only the high burden of CAD but also its...