SCREENING PHYTOCHEMICAL ANDANTI-METHICILLIN RESISTANT (MRSA)ACTIVITY OF 70 % ETHANOLIC EXTRACT FROM THE STEM BARK OF ALBIZIA LEBBECK(L.) BENTH.(FABACEAE)
Journal Title: Asian Journal Of Pharmaceutical Research and Development - Year 2018, Vol 6, Issue 6
Abstract
The emergence of multi-drug resistant strains and limitations of present antimicrobial drugs have led to continuous search for natural products as curative agents for Anti-methicillin resistantinfections. The aim of this study was to evaluate antibacterialactivity of an ethanolic extract from Albizia lebbeckstem bark against Anti-methicillin resistant. Methods and Results: The methods of dissemination swab on muller-hinton agar and double dilution were used to evaluate the antibacterial activity of 70 % ethanolic extract of stem bark of Albizia lebbeck.All multi-resistant strains of Staphylococcus aureusand the reference strain (ATCC 25923) were sensitive to 70 % ethanolic extract of the stem bark of Albizia lebbeck. The MBCvary from 0,49 mg/mL to 2mg/mL.Also, the phytochemical screening of this extract revealed the presence of Polyphenols, Gallic tannins, Catechin tanninsand Flavonoids. These findings confirm that an 70 % ethanolic extract from Albizia lebbeck stem bark inhibited growth of Anti-methicillin resistantat low concentration and could be utilised as an alternative Anti-methicillin resistant agent
Authors and Affiliations
Yao Kanga, Djeneb Camara, Kouadio Aubin Kouassi, Guédé Noël Zirihi
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