Search of the promising species of subfamily Amygdaloideae and Pyroideae using the chemotaxonomy
Journal Title: ScienceRise: Pharmaceutical Science - Year 2018, Vol 0, Issue 6
Abstract
<p>World flora has more than 1000 species of the genus Сrataegus L., more than 30 species belong to the subgenus Prunus L., genus Malus Mill. has 100 species, subgenus Cerasus Juss. includes more than 150 species. Despite the diversity of species and a sufficient resource base, only a few representatives of the genus sufficiently researched and found their use as sources of biologically active substances (BAS).</p><p><strong>Aim</strong><strong> </strong><strong>of</strong><strong> </strong><strong>research</strong><strong>. </strong>To conduct a chemotaxonomic study of representatives of the genus Сrataegus L., Prunus L., Malus Mill., Cerasus Juss.; to establish a promising sources of biologically active substances for the drugs production.</p><p><strong>Materials</strong><strong> </strong><strong>and</strong><strong> </strong><strong>methods</strong><strong>. </strong>Chemotaxonomic study was carried out using the method of the graph analysis. The chemomarkers were phenolic compounds and terpenoids, identified in the generative and vegetative organs of the representatives of the genus Сrataegus L., Prunus L., Malus Mill., Cerasus Juss. The terpenoids and organic acids were identified by a chromatography-mass-spectrometric method on an Agilent Technology 6890N chromatograph with a 5973N mass-spectrometric detector. Flavonoids and hydroxycinnamic acids were detected by chromatography.</p><p><strong>Results</strong><strong>. </strong>The chemical profiles of vegetative and generative organs of 34 species of the genus Сrataegus L. are established, 5 species of the genus Prunus L., 7 species of the genus Malus Mill., 4 species of the genus Cerasus Juss. The promising species of hawthorn, wich accumulated a general group BAS of genus was detected.</p><p><strong>Conclusion</strong><strong>. </strong>According to the results of a chemotaxonomic study of representatives of subgenus Amygdaloideae and Pyroideae was detected a promising sources of biologically active substances (BAS) among species of the genus Crataegus L., Prunus L., Malus Mill. and Cerasus Juss. The chemical profiles are forming flavonoids, terpenoids and aromatic acids. The promising species of hawthorn was added to the complex «Kratophyt»</p>
Authors and Affiliations
Natalia Sydora, Alla Kovaleva, Alexandr Goncharov
Keywords
Related Articles
- EP ID EP526863
- DOI 10.15587/2519-4852.2018.153199
- Views 180
- Downloads 0
Study of the morphologo-anatomic signs of shoots of the Salix caprea L. of Ukrainian flora
<p>Representatives of the Salicaceae family are valuable sources of medicinal plant material that has long been used in traditional medicine in many countries around the world. In European countries, some willow species...
Наукове обґрунтування моделі розробки рекомендованого переліку лікарських засобів для фармакотерапії гострого бронхіту у дітей раннього віку
<p>Важливим напрямом реалізації державної політики кожної країни є забезпечення виконання соціальних стандартів галузі охорони здоров’я, зокрема в аспекті фармацевтичного забезпечення декретованих категорій населення без...
Standardization parameters of modified extracts from leonurus cardiaca herb
<p>To date, in Ukraine there are 8 combined herbal medicines of Leonurus cardiaca registered in Ukraine, 10 national enterprises produce tincture of it and 3 national manufactures pack it herb. Tincture of Leonurus cardi...
Study of the inulin complex of dahlia root bulbs of Ken's flame species and its standardization
<p>The literature data analysis has shown that phytopolysaccharides are perspective sources for study and development of active pharmaceutical ingredients, and can be used as new medicines or biologically active additive...
Study of superoxide- and NO-dependent protective mechanisms of N-acetylcysteine and losartan in ratʼs aorta and liver under streptozoticin-induced type 1 diabetes mellitus
<p><strong>Aim.</strong> The aim of the research was to investigate superoxide- (SR) and NO-dependent mechanisms of action of N-acetylcysteine (NAC) and losartan (LOS) in aorta and liver of rats with type 1 diabetes mell...