SEMICARBAZONE DERIVATIVES AND THEIR PHARMACOLOGICAL ACTIVITIES
Journal Title: World Journal of Pharmaceutical Research - Year 2018, Vol 7, Issue 3
Abstract
Epilepsy can be devastating to patient’s day to day life. Different categories of antiepileptic agents are present in market but they have toxic effects on central nervous system. Aryl and heteroaryl semicarbazone derivatives present a new area of interest as anticonvulsant drugs. Semicarbazones have been widely synthesized for their anticonvulsant properties. Many semicarbazones have shown better activity and low neurotoxicity than already available drugs, therefore they can be used as lead compounds for the synthesis of newer antiepileptics. Various semicarbazones have been synthesized which possess different pharmacological activity in addition to antiepileptic activity.
Authors and Affiliations
Suman Lata Rawat
Keywords
Related Articles
- EP ID EP620124
- DOI -
- Views 135
- Downloads 0
ANALYSIS OF THE EFFECT OF STEVIOL VS. NITROGEN BASES OF RNA AND DNA USING QUANTUM METHODS
The main component of the Stevia (STV) is steviol [(5β,8α,9β,10α,13α)-13-Hydroxykaur-16-en-18-oic acid]. In recent years Stevia (STV) has aroused the interest of researchers due to high human consumption as an artificial...
MULTISYSTEM LANGERHANS CELL HISTIOCYTOSIS: CASE REPORT AND REVIEW OF THE LITERATURE
Langerhans cell histiocytosis (LCH) is a rare and heterogeneous disease of unknown etiopathogenesis caused by clonal proliferation of Langerhans cells. We report a case of an adult woman diagnosed with Langerhans cell hi...
AVOIDANCE OF COMPLICATIONS DURING CABG
Objective: To review the incidence of stroke in patients undergoing CABG and the impact of a preventive strategy adopted at tertiary care unit of cardiac surgery. Methods: The data of all patients who underwent isolated...
AAHAR PARINAMKAR BHAVAS IN AYURVEDA: A REVIEW STUDY
According to Ayurveda Dosha, Dhatu and Mala are roots of body. The balanced state of dosha, dhatu and mala reflects the healthy state of body and its unbalanced state reflects disease. The balanced state of these dosha d...
SUBCHRONIC EVALUATION OF THE ETHANOL STEM BARK EXTRACT OF ENANTIA CHLORANTHA IN RODENTS (BIOCHEMICAL, HAEMATOLOGICAL EVALUATION AND EFFECT ON BODY WEIGHT)
Enantia chlorantha is a medicinal plant used to treat malaria and other febrile illnesses in the southern and other parts of Nigeria. Aim of study: To determine the biochemical and haematological properties of ethanolic...