SEMICARBAZONE DERIVATIVES AND THEIR PHARMACOLOGICAL ACTIVITIES
Journal Title: World Journal of Pharmaceutical Research - Year 2018, Vol 7, Issue 3
Abstract
Epilepsy can be devastating to patient’s day to day life. Different categories of antiepileptic agents are present in market but they have toxic effects on central nervous system. Aryl and heteroaryl semicarbazone derivatives present a new area of interest as anticonvulsant drugs. Semicarbazones have been widely synthesized for their anticonvulsant properties. Many semicarbazones have shown better activity and low neurotoxicity than already available drugs, therefore they can be used as lead compounds for the synthesis of newer antiepileptics. Various semicarbazones have been synthesized which possess different pharmacological activity in addition to antiepileptic activity.
Authors and Affiliations
Suman Lata Rawat
Keywords
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