Senior Resident, Department of Paediatrics, Rangaraya Medical College/Government General Hospital, Kakinada

Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 82

Abstract

BACKGROUND Although CNS tumours are not common (<1.5% of all cancers) in comparison with tumours of other organs (e.g., lung, breast, or colon), they deserve a unique position in tumour oncology because of their histopathologic complexity and biologic behaviour. Topographical and histological classifications, as well as correlations of topography to pathology, serve for the better studying, understanding, and handling of brain tumours. Aim- This study was undertaken to study the imaging findings of intracranial tumours and to compare them with the histopathological diagnosis. MATERIALS AND METHODS This is a prospective study, a minimum of 50 patients with signs and symptoms of intracranial tumours referred to the Department of Radiodiagnosis in Kurnool Medical College. All the patients with suspected intracranial tumours underwent Plain and Contrast Computed tomography of Brain on 16 slice GE bright speed CT. Plain and contrast MRI was done for all the patients on XGY 0.35 Tesla. Histopathology examination was done by using Haematoxylin & Eosin stain in the Department of Pathology, Kurnool Medical College. Inclusion Criteria- Patients with signs and symptoms of intracranial tumours between all the age groups are included. Exclusion Criteria- Patients for whom CT or MRI could not be performed due to raised serum creatinine levels, pregnancy, claustrophobia, metal implants and cardiac pacemakers. Patients for whom surgery or HPE was not done are excluded. RESULTS In the present study out of 50 cases, meningiomas accounted for 18 cases, followed by Astrocytomas accounting for 17 cases and Schwannoma and Tuberculomas with 3 cases each. There are 2 cases of Pituitary macroadenoma, 2 cases of craniopharyngioma, one case of oligoastrocytoma, oligodendroglioma/Subependymoma, secondaries, medulloblastoma each. The Sensitivity, Specificity, Positive predictive value, Negative predictive value and p value of CT are 95.35%, 28.57%, 89.13%, and 50%, 0.03 (significant) respectively. The Sensitivity, Specificity, Positive predictive value, Negative predictive value and p value of MRI are 97.78%, 40%, 93.16%, 66%, 0.0007 (significant) respectively. CONCLUSION Imaging plays an important role in the diagnosis of intracranial tumours. Compared to CT, MRI has a greater role in accurately diagnosing the intracranial tumours with few false negative and false positive cases.

Authors and Affiliations

Jamkhana Abdul Gafoor, Onteddu Joji Reddy, Balla Suresh, Harinath D, Bandi Arun Kumar

Keywords

Related Articles

ESTIMATION OF SERUM VITAMIN D LEVELS AT TERM PREGNANCY IN A TERTIARY CARE CENTRE IN EASTERN INDIA- A CROSS-SECTIONAL STUDY

Vitamin D3 deficiency is very common in pregnant women in India, despite India being a tropical country. Keeping in mind the large percentage of mothers affected by vitamin D3 deficiency, routine antenatal vitamin D3 est...

ASSESSMENT OF COLORECTAL CARCINOMA WITH EMPHASIS ON OUTCOME OF YOUNG AGED PATIENTS- A STUDY OF 62 CASES

BACKGROUND Colorectal Carcinoma (CRC) is an upcoming aggressive malignancy, especially among young adult population in recent years. This study emphasises on assessing disease burden and its outcome in young age colorect...

LONG-TERM CHANGES IN THICKNESS OF BICEPS TENDON AND ROTATOR CUFF AT DIFFERENT STAGES OF FUNCTIONAL RECOVERY OF HEMIPLEGIC SHOULDER- AN OBSERVATIONAL STUDY

BACKGROUND Shoulder pain and stiffness is a common problem after stroke. Many types of shoulder pathology after stroke have been reported. Ultrasonography can diagnose most of the pathologies in and around the shoulder....

&nbsp;HISTOMORPHOLOGICAL STUDY OF PAEDIATRIC LIVER TUMOURS-A SINGLE INSTITUTION EXPERIENCE

[b]&nbsp;INTRODUCTION[/b]: Liver tumours are uncommon in infancy and childhood, accounting to 1-2% of all paediatric neoplasms. Though rare, 2/3rds of cases unfold as malignancies. These neoplasms differ considerably...

&nbsp;THE ROLE OF SYNOVECTOMY IN TOTAL KNEE ARTHROPLASTY: A PROSPECTIVE ANALYSIS OF 30 CASES

&nbsp;AIM AND OBJECTIVES Aim and objective of this study is to assess role of synovectomy during TKR on joint effusion, haemarthrosis, patellar clunk, recurrent synovitis, and histopathological diagnosis in patients u...

Download PDF file
  • EP ID EP276096
  • DOI 10.14260/jemds/2017/1251
  • Views 75
  • Downloads 0

How To Cite

Jamkhana Abdul Gafoor, Onteddu Joji Reddy, Balla Suresh, Harinath D, Bandi Arun Kumar (2017). Senior Resident, Department of Paediatrics, Rangaraya Medical College/Government General Hospital, Kakinada. Journal of Evolution of Medical and Dental Sciences, 6(82), 5768-5771. https://europub.co.uk/articles/-A-276096