SENSORY IMPROVEMENT AND REDUCTION OF NERVE THICKENING IN A LEPROSY PATIENT TREATED WITH ULTRASOUND GUIDED PERINEURAL INJECTION OF AUTOLOGOUS PLATELETRICH PLASMA: A CASE REPORT AND REVIEW OF LITERATURE.
Journal Title: International Journal of Advanced Research (IJAR) - Year 2019, Vol 7, Issue 4
Abstract
Background: Leprosy is caused by Mycobacterium leprae which has a certain predilection for peripheral nerves. It causes peripheral neuropathy and in the long run, it causes deformity of hands and feet. Platelet-rich plasma (PRP) which contains a variety of growth factors can stimulate neural regeneration. Materials & Methodology:A case report and review of literature (PubMed, Embase, Google Scholars, and other electronic search engines) were done. In a 45-year-old male leprosy patient, ultrasound-guided perineural autologous PRP (1 ml) injection was given at the right ulnar nerve under all aseptic precautions. Results: Right ulnar nerve showed sensory improvement especially in ulnar distribution. In ultrasound, right ulnar nerve showed mild reduction in mean cross-sectional area whereas the left ulnar nerve showed no changes. Interventions which were ethically supported by existing literature and evidences were followed and reviewed. Conclusion: To the best of our knowledge, this is the first case report where ultrasound-guided intervention was done, a long term follow-up for 4 weeks was followed and nerve thickness comparison was done. Here, PRP showed its promising role to reduce the nerve thickness and to improve the sensory function in leprosy.
Authors and Affiliations
Raktim Swarnakar, Hafis Rahman.
Keywords
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- EP ID EP565089
- DOI 10.21474/IJAR01/8847
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