Sentinel Lymph Node Biopsy A new approach in the management of head and neck cancers
Journal Title: Sultan Qaboos University Medical Journal - Year 2017, Vol 17, Issue 1
Abstract
Cervical lymph node metastasis affects the prognosis and overall survival rate of and therapeutic planning for patients with head and neck squamous cell carcinomas (HNSCCs). However, advanced diagnostic modalities still lack accuracy in detecting occult neck metastasis. A sentinel lymph node biopsy is a minimally invasive auxiliary method for assessing the presence of occult metastatic disease in a patient with a clinically negative neck. Tis technique increases the specifcity of neck dissection and thus reduces morbidity among oral cancer patients. Te removal of sentinel nodes and dissection of the levels between the primary tumour and the sentinel node or the irradiation of target nodal basins is favoured as a selective treatment approach; this technique has the potential to become the new standard of care for patients with HNSCCs. Tis article presents an update on clinical applications and novel developments in this feld.
Authors and Affiliations
Deepti Sharma| Department of Oral & Maxillofacial Pathology, Christian Dental College & Hospital, Ludhiana, Punjab, India, George Koshy| Department of Oral & Maxillofacial Pathology, Christian Dental College & Hospital, Ludhiana, Punjab, India, Sonal Grover| Department of Oral & Maxillofacial Pathology, Christian Dental College & Hospital, Ludhiana, Punjab, India, Bhushan Sharma| Department of Oral & Maxillofacial Pathology, Christian Dental College & Hospital, Ludhiana, Punjab, India
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