Sero-prevalence of Hepatitis B Infection and Its Risk Factors among Women Admitted for Delivery in Ucth, Calabar, Nigeria
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2015, Vol 8, Issue 4
Abstract
Background: Vertical transmission of hepatitis B virus infection during pregnancy and delivery remains the major route of transmission in low resource areas. The objectives of this study were to determine the sero-prevalence of hepatitis B infection (HBsAg) and the potential risk factors among pregnant women admitted for delivery. Materials and Methods: This cross-sectional study of 300 women admitted for delivery was conducted at University of Calabar Teaching Hospital, Calabar, Nigeria. A pretested questionnaire was used for the collection of socio-demographic data and possible risk factors. Blood sample was collected from each consented woman and the plasma tested for the presence of HBsAg using rapid ELISA test Kits in the laboratory of the hospital. All the data were analyzed using microsoft SPSS version 17 statistical program. Results: Out of the 300 women studied, positive HBsAg was detected in 14 women, giving a sero-prevalence rate of 4.7%. The age of the women studied varied from 16 to 43 years with mean age of 27.9±4.6 years and mean parity of 1.1±1.5. Hepatitis B viral infection was significantly higher among pregnant women who did not attend any antenatal care (unbooked women) than pregnant women who attended antenatal care (booked women). There were statistically significant relationships between HBV infection and 2 or more sexual partners and previous history of induced abortion. Previous histories of blood transfusion, previous surgeries/dental manipulations, tribal marks/tattoos, previous contact with somebody with hepatitis B infection were not statistically significant. The data are related to 14 (4.7%) of HBV infected women in the study. Conclusion: An intermediate prevalence of hepatitis B virus infection was identified which justifies the need for routine screening in pregnancy especially among unbooked women in order to identify and treat the infection.
Authors and Affiliations
C. U. Iklaki, C. I. Emechebe, B. U. Ago, C. O. Njoku
Keywords
Related Articles
- EP ID EP347848
- DOI 10.9734/BJMMR/2015/16397
- Views 59
- Downloads 0
Patients with Abdominal Aortic Aneurysm Demonstrate Higher Levels of Non-cholesterol Sterol Markers of Endogenous Cholesterol Synthesis
Aims: To establish the levels of selected non-cholesterol sterols in patients with abdominal aortic aneurysm (AAA) and to compare them with levels in non-AAA patients treated for lipid metabolism disorder. To compare the...
Socio-Demographic Characteristics and Predictors of Childhood Primary Nocturnal Enuresis in Benin City, Nigeria
Aim: To document the socio-demographic characteristics and predictors of primary nocturnal enuresis in children. Study Design: A descriptive cross sectional study. Place and Duration of Study: The study was carried out...
Endothelial Dysfunction and Cardiovascular Disease: Critical Target for Cell-Based Therapies
This review briefly summarizes how cell-based therapeutic interventions are being developed and applied to treat endothelial dysfunction (ED) as a critical clinical target. ED directly contributes to the onset and progno...
Fertility Desire and Reproductive Health Education Needs of Women Living with HIV Receiving Care at Regional Hospital Limbe HIV Treatment Centre
Aims: Fertility desires among persons living with HIV (PLHIV) could have important HIV prevention and demographic implications particularly in high prevalence settings such as Cameroon. There is a paucity of data on fert...
Heparin Inhibits Proliferation and Migration of Patient-Derived Vascular Cells Only at Non-physiological Concentrations Due to Antagonistic Pathways
Aims: Experimental animal models have demonstrated inhibition of intimal hyperplasia processes by heparin. These effects have not been observed in clinical trials. Diverging experimental conditions are the most conspicuo...