Sero Prevalence of Leptospirosis Among Fever Cases (PUO) Reported from Guntur Government Hospital in And Around Guntur District, Andhra Pradesh, India.
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 12
Abstract
Objective: To determine the seroprevalence of leptospirosis among febrile inpatient cases in Guntur Government Hospital, Guntur. Methods: A hospital-based cross-sectional study was conducted among 100 febrile cases admitted to Guntur Government Hospital in Guntur. A survey using a proforma sheet was used to obtain sociodemographic and occupational information. Serum samples were screened for leptospirosis by IgM and IgG enzyme-linked immunosorbent assay test (IgM &IgG ELISA). Results: Antibodies to leptospires were detected in 48 samples for IgM (48%) and 18 samples for IgG(18%) giving an overall seroprevalence of 66%. The seroprevalence was highest among agriculture workers (53.03%) followed by sewage workers (18.1%)), animal handlers (16.6%) butchers (9.09%) and forest workers (3.03%), Seropositivity of Leptospira IgM and IgG antibodies was found higher among males than females (41% vs. 25%). The highest Leptospira antibodies seropositivity was detected in elderly and in rural area patients. Conclusions: This study revealed a possible high seroprevalence of leptospirosis among febrile cases, indicating the need to review the importance of adding leptospirosis to the case investigation of febrile illness, especially among high-risk occupational groups in and around Guntur. Leptospirosis is a severe spirochetal zoonosis in the world. It is considered an occupational disease of persons engaged in agriculture, sewage works, forestry, and animal slaughtering. A study was conducted with an objective of assessing the seroprevalence of leptospirosis among the high-risk groups in and around Guntur. A total of 100 sera samples from different high-risk populations with fever were collected and tested by ELISA for IgM and IgG antibodies. Antibodies to leptospires were detected in 48 samples for IgM and 18 samples for IgG giving an overall seroprevalence of 66%. The seroprevalence was highest among agriculture workers (53.03%) followed by sewage workers (18.1%), animal handlers (16.6%), forest workers (3.03%), and butchers (9.09%). .Seropositivity of Leptospira antibodies was found higher among males than females (41% vs. 25%). The highest Leptospira antibodies seropositivity was detected in elderly patients and in rural patients. Conclusion: Individuals engaged in risk activities are often exposed to leptospiral infection. Therefore, control and prevention policy toward these people are necessary.
Authors and Affiliations
Dr. B. V. Sivamma M. D
Keywords
Related Articles
- EP ID EP250754
- DOI 10.9790/0853-1612051215
- Views 65
- Downloads 0
Uterine Arteriovenous Malformations
Background: Uterine arteriovenous malformation (AVM) is an uncommon vascular disease, which can be a life-threatening condition. Treatment recommendations include embolization versus hysterectomy. Case: A 26 year-old gra...
Prevalence And Patterns of Maxillofacial Trauma in South India - A Retrospective Study For Seven Years.
Abstract: Maxillofacial trauma is a complex fracture involving jaws and dentition. Documentation of these fractures are of paramount importance for improving patient care and development of infrastructure especially road...
Smoking Related Knowledge, Attitude And Prevalence Among Medical Students In Princess Noura University
Smoking has been increasing in Saudi Arabia particularly among college and university students specially female students. Yet there is no enough information related to smoking leading factors and reasons behind adopting...
A study of comparison of fasting blood glucose level and postprandial blood glucose level v/s HbA1c level for long term control of diabetes: An observational study
Introduction: Diabetes mellitus is a noncommunicable disease which is most prevalent and has become a modern epidemic. For many times, diabetes was diagnosed based on plasma glucose criteria, either the fasting blood sug...
Study of Pathological Lesions in Liver Autopsy
Liver is a site for plethora of disease among which many become symptomatic. However, some are diagnosed only on autopsy examination. Our aim is to correlate gross and histopathological examination of 109 liver autopsy s...