Seroepidemiology and Gender Related Differences in Laboratory Characteristics of Dengue Virus Infection: A Hospital Based Study, Bhopal
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 1
Abstract
Introduction: Data regarding gender related differences in serological and haematological findings of dengue infection is lacking in Indian settings especially in Central part of India where dengue is endemic. Objectives: To study seroepidemiology and association of serological and haematological findings with gender in dengue seopositive patients. Methods: 1071 dengue suspected patients attending to hospital from 1st January 2014 to 31st December 2015 were included. Their serum samples were tested for NS1 antigen and IgM and IgG antibodies by immunochromatographic test. Total leucocytes count (TLC) and platelet counts of seropositive patients were noted. Association of laboratory findings were correlated with gender by using Chi-square test and P value was obtained. Results and Discussion: 16.43% samples were found to be seropositive with Male:Female ratio 1:0.76. Maximum seropositivity was detected in 21-30 years. 69.31% were primary and 17.04% seropositive cases were labelled as secondary dengue infection. 13.63% IgM+IgG positive samples couldn’t be classified. Thrombocytopenia and and leucopoenia was detected in 75(42.61%) and 69(39.20 %) dengue seropositive cases respectively. No significant association was found in haematological findings with gender (P >0.05). Conclusions: The current study found a consistent pattern of male predominance and young age. High index of suspicion of severe dengue fever should be maintained in all patients irrespective of gender.
Authors and Affiliations
Dr. Shashwati Nema, Dr. Amit Deol, Dr. Kiran Tripathi, Dr. V. K. Ramnani
Keywords
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- EP ID EP589016
- DOI 10.9790/0853-1601049599
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