Serological Study on Mucosal Response of Cattle to Haemorrhagic Septicaemia Vaccine

Journal Title: Global Journal of Animal Scientific Research - Year 2014, Vol 2, Issue 4

Abstract

The purpose of this study was to compare the efficacies of systemic immune response to mucosal vaccination against Pasteurella multocida infection in cattle. Three groups of ten cattle each were immunized subcutaneously and intranasally with bacterin of P. multocida serotype B: 2. Group 1 and Group 2 were immunized subcutaneously and intranasally with 0.5 ml of bacterin mixed with mucosal adjuvant respectively. Group 3 served as a control group was immunized subcutaneously with 1 ml of final vaccine product of bacterin as recommended dose according to Central Veterinary Research Laboratories, two cattle for each group unvaccinated control, all three groups received a booster dose on day 24 post inoculation.The level of the antibody immune response in these three groups was measured by the indirect haemagglutination test. Serum and nasal antibodies of vaccinated animals increased after the second vaccination, and this difference was statistically significant. Concentration of serum antibody against P. multocida increased from primary vaccination (6.25 antibody titer) on day 7 to (82.5 antibody titer) on day 31 after boosting animal, similar levels of protection were obtained from group 3. The nasal antibodies were rised from (3.75 antibody titer) at first vaccination on day 7 to (20 antibody titer) on day 31 after the second inoculation. The mucosal level of antibody in the intranasally vaccinated group was less compared to subcutaneously vaccinated group.

Authors and Affiliations

Mortada Mohammed Abbakar Yagoub, K. M. Suleiman

Keywords

Related Articles

Sheep and Goat Marketing and Consumption in Relation To Religious Festivities in Shifting and Permanent Farming Systems in Western Ethiopia

This study explored sheep and goat marketing and consumption in shifting farming system (SFS) and permanent farming system (PFS) in relation to festivities in Western Ethiopia. A cross-sectional random survey involving...

Characteristics of the First Record of Bat (Mammalia: Chiroptera) Fauna from Peshawar and Adjacent Areas, Khyber Pakhtunkhwa, Pakistan

The present research was conducted to explore the bat fauna of districts Charsadda, Kohat, Mardan and Nowshera, Khyber Pakhtunkhwa, Pakistan during July 2011 to May 2013. A total of (N=213) bats of 5 genera and 10 spe...

Assessment of Udder Size and Milk Yield of West African Dwarf (Wad) Goats Reared Under Semi Intensive Management System in Humid Nigeria

Studies on udder size of twenty lactating doe of West African Dwarf (WAD) goats were conducted to determine their Partial Daily Milk yield (PDM). Data were collected for the first twenty five days of lactation on daily...

Development of Dry Season Supplements for Ruminants and Their Degradation Characteristics in the Semi Arid of Nigeria

This experiment was conducted to develop dry season supplement for ruminants and their degradation characteristics. Ten (10) different rations were formulated, F1, F2, F3, F4, F5, F6, F7, F8, F9, and F10 using a mixtur...

Evaluation of Carcass Characteristics and Meat Quality of Indigenous Fowl Ecotypes and Exotic Broiler Strains Raised Under Hot Climate

This study was conducted to investigate the influence of genotype on growth performance, carcass characteristics and meat chemical composition traits of chickens under hot climatic conditions. Two exotic meat strains (...

Download PDF file
  • EP ID EP29055
  • DOI -
  • Views 342
  • Downloads 6

How To Cite

Mortada Mohammed Abbakar Yagoub, K. M. Suleiman (2014). Serological Study on Mucosal Response of Cattle to Haemorrhagic Septicaemia Vaccine. Global Journal of Animal Scientific Research, 2(4), -. https://europub.co.uk/articles/-A-29055