Seroprevalence and trend of Hepatitis B virus infection among the blood donors of North Karnataka: A Nine Year Study
Journal Title: Pathology Update: Tropical Journal of Pathology and Microbiology - Year 2017, Vol 3, Issue 3
Abstract
Introduction: Hepatitis B is one of the leading transfusion transmissible infections. The prevalence of this infection varies across the different geographical areas with intermediate prevalence in India. Studying the trend in seroprevalence is useful to assist the preventive strategies. The aim of this study was to determine the trend of seroprevalence of hepatitis B in North Karnataka region over a nine-year period (2007-2015). Materials & Methodology: The study was conducted at one of the largest blood banks of Northern Karnataka of an apex health care institution serving predominantly the people of North Karnataka. A retrospective analysis of blood donors over a period of nine years (2007-2015) was done to assess the seroprevalence and the trend of hepatitis B infection among them. ELISA was used to detect the hepatitis B surface antigen in the donors as a marker of infection. Results: A total of 80,312 blood donors were undertaken for the study. About 1613 (2%) were positive for HBsAg, which falls under the “intermediate prevalence (2%-7%) zone” as per World Health Organization (WHO) guidelines. An increasing trend in first five years (2007-2011) and then decreasing trend over next four years (2012-2015) was observed in the present study. Replacement donors and male blood donors showed significantly higher seropositivity compared to voluntary donors and female donors respectively. Conclusion: North Karnataka has an intermediate prevalence of hepatitis B in blood donors with increasing trend in initial five years and decreasing trend over the last four-year period.
Authors and Affiliations
Sujata S. Giriyan, Niraj Kumar Nirala, Akansha Agrawal, Richa Bajpai
Keywords
Related Articles
- EP ID EP264185
- DOI 10.17511/jopm.2017.i3.03
- Views 132
- Downloads 0
Ovarian mass lesions: evaluation of ultrasound guided fine needle aspiration cytology with histopathological correlation
Background: Ovarian masses are frequent finding in females of reproductive age group. Image-guided fine-needle aspiration cytology (FNAC) of ovarian lumps is being increasingly used for the successful diagnosis of ovaria...
A prospective study of the palpable lesions of the breast and the role of FNAC in these lesions with available histopathology methods
Introduction: Benign as well as malignant breast lesions are quite common in Indian population. It is the second most common cancer site after cancer cervix. Fine-needle aspiration cytology (FNAC) is safe, reliable, and...
Seroprevalence and trend of Hepatitis B virus infection among the blood donors of North Karnataka: A Nine Year Study
Introduction: Hepatitis B is one of the leading transfusion transmissible infections. The prevalence of this infection varies across the different geographical areas with intermediate prevalence in India. Studying the tr...
Comparison of different cytological tools with conventional diagnostic methods in diagnosis of Helicobacter pylori infection
Background: Helicobacter Pylori (H pylori) infection causes severe gastrointestinal morbidity and mortality worldwide. Objective: To evaluate the usefulness of gastric crush cytology and imprint cytology with conventiona...
Evaluation of Helicobacter pylori stool antigen test in comparison with conventional methods in detection of helicobacter pylori infection in dyspepsia patients
Background: Helicobacter pylori colonize the human stomach and is associated with gastritis, gastric and duodenal ulcers, gastric adenocarcinoma and mucosa associated lymphoid tissue lymphoma. Owing to its momentous path...