Seroprevalence of Hepatitis A and E Virus IgM in Children Suffering from Acute Hepatitis
Journal Title: Journal of Medical Science And clinical Research - Year 2015, Vol 3, Issue 3
Abstract
Objective: Acute viral hepatitis (AVH) in children is a major health problem, among which feco-orally transmitted hepatitis A and hepatitis E are major public health problem in developing countries like India. Their incidence, severity and outcome in small children in central India is not well known Methods: Prospective cross sectional study in which children with acute viral hepatitis were analysed for hepatitis A and hepatitis E IgM by ELISA. Results: A total of 70 patients were included in the study, out of which 11 (15.7%) patients were positive for hepatitis A, whereas 7(10%) patients were positive for hepatitis E and 2 (2.8%) patients were positive for recent infection of both hepatitis A and hepatitis E. Male preponderance was noted. Acute liver failure (ALF) was seen more often in HAV infection. Conclusion: AVH is a significant problem in central India. Co-infection of hepatitis viruses is not infrequent and detected in many cases.
Authors and Affiliations
Dr Sumit Kumar Rawat
Keywords
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